EC number:1.6.5.11
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.6 Acting on NADH or NADPH |
| 1.6.5 With a quinone or similar compound as acceptor |
| ID: | 1.6.5.11 |
|---|---|
| Description: | NADH dehydrogenase (quinone). |
| Cath: | 1.10.10.1590; 1.10.287.3510; 1.10.645.20; 1.20.120.1200; 1.20.1440.230; 1.20.5.270; 1.20.5.2700; 1.20.5.30; 1.20.5.3060; 3.30.110.40; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.6.5.11 |
| BRENDA Enzyme Link: | BRENDA 1.6.5.11 |
| KEGG Enzyme Link: | KEGG1.6.5.11 |
| BioCyc Enzyme Link: | BioCyc 1.6.5.11 |
| ExPASy Enzyme Link: | ExPASy1.6.5.11 |
| EC2PDB Enzyme Link: | EC2PDB 1.6.5.11 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.6.5.11 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.6.5.11 |
| IntEnz Enzyme Link: | IntEnz 1.6.5.11 |
| MEDLINE Enzyme Link: | MEDLINE 1.6.5.11 |
| RHEA:46160 | a quinone + H(+) + NADH = a quinol + NAD(+) |
| RULE(radius=1) | [*:1]-[N;H0;+0:2]1-[CH;+0:3]=[C;H0;+0:4](-[*:5])-[CH2;+0:6]-[CH;+0:7]=[CH;+0:8]-1.[H+;H0:9].[O;H0;+0:10]=[C;H0;+0:11]1-[CH;+0:12]=[CH;+0:13]-[C;H0;+0:14](=[O;H0;+0:15])-[CH;+0:16]=[CH;+0:17]-1>>[*:1]-[n+;H0:2]1:[cH;+0:3]:[c;H0;+0:4](-[*:5]):[cH;+0:6]:[cH;+0:7]:[cH;+0:8]:1.[OH;+0:10]-[c;H0;+0:11]1:[cH;+0:12]:[cH;+0:13]:[c;H0;+0:14](-[OH;+0:15]):[cH;+0:16]:[cH;+0:17]:1 |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Characterization of the overproduced NADH dehydrogenase fragment of the NADH:ubiquinone oxidoreductase (complex I) from Escherichia coli. | Braun M, Bungert S, Friedrich T | 1998 Feb 17 | 9485311 |
| The three-dimensional structure of NAD(P)H:quinone reductase, a flavoprotein involved in cancer chemoprotection and chemotherapy: mechanism of the two-electron reduction. | Li R, Bianchet MA, Talalay P, Amzel LM | 1995 Sep 12 | 7568029 |
| Effects of weight cycling on metabolic control in male outpatients with non-insulin-dependent diabetes mellitus. | Schotte DE, Cohen E, Singh SP | 1990 | 2226388 |
| Characterization and partial purification of microsomal NAD(P)H:quinone oxidoreductases. | Jaiswal AK | 2000 Mar 1 | 10683249 |