Enzyme

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EC Tree
     1. Oxidoreductases
        1.7 Acting on other nitrogenous compounds as donors
            1.7.2 With a cytochrome as acceptor
ID:1.7.2.5
Description:Nitric-oxide reductase (cytochrome c).
Cath: 1.10.760.10; 1.20.210.10;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.7.2.5
BRENDA Enzyme Link: BRENDA 1.7.2.5
KEGG Enzyme Link: KEGG1.7.2.5
BioCyc Enzyme Link: BioCyc 1.7.2.5
ExPASy Enzyme Link: ExPASy1.7.2.5
EC2PDB Enzyme Link: EC2PDB 1.7.2.5
ExplorEnz Enzyme Link: ExplorEnz 1.7.2.5
PRIAM enzyme-specific profiles Link: PRIAM 1.7.2.5
IntEnz Enzyme Link: IntEnz 1.7.2.5
MEDLINE Enzyme Link: MEDLINE 1.7.2.5
MSA:

1.7.2.5;

Phylogenetic Tree:

1.7.2.5;

Uniprot:
M-CSA:
RHEA:30211 2 [Fe(III)cytochrome c] + H2O + nitrous oxide = 2 [Fe(II)cytochrome c] + 2 H(+) + 2 nitric oxide
RULE(radius=1) [Fe+3;H0:1].[Fe+3;H0:2].[N;H0;+0:3]#[N+;H0:4]-[OH;+0:5].[OH2;+0:6]>>[Fe+2;H0:1].[Fe+2;H0:2].[NH;+0:4]=[O;H0;+0:5].[NH;+0:3]=[O;H0;+0:6]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Formation of the N-N bond from nitric oxide by a membrane-bound cytochrome bc complex of nitrate-respiring (denitrifying) Pseudomonas stutzeri.Heiss B, Frunzke K, Zumft WG1989 Jun2542222
The active site of the bacterial nitric oxide reductase is a dinuclear iron center.Hendriks J, Warne A, Gohlke U, Haltia T, Ludovici C, Lübben M, Saraste M1998 Sep 229748316
From NO to OO: nitric oxide and dioxygen in bacterial respiration.Hendriks J, Gohlke U, Saraste M1998 Feb9623801
The MCD and EPR of the heme centers of nitric oxide reductase from Pseudomonas stutzeri: evidence that the enzyme is structurally related to the heme-copper oxidases.Cheesman MR, Zumft WG, Thomson AJ1998 Mar 179521721
Structural basis of biological N2O generation by bacterial nitric oxide reductase.Hino T, Matsumoto Y, Nagano S, Sugimoto H, Fukumori Y, Murata T, Iwata S, Shiro Y2010 Dec 1721109633
NO reduction by nitric-oxide reductase from denitrifying bacterium Pseudomonas aeruginosa: characterization of reaction intermediates that appear in the single turnover cycle.Kumita H, Matsuura K, Hino T, Takahashi S, Hori H, Fukumori Y, Morishima I, Shiro Y2004 Dec 3115504726