EC number:1.7.3.3
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.7 Acting on other nitrogenous compounds as donors |
| 1.7.3 With oxygen as acceptor |
3D structure
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1XY3;
1R56;
1XXJ;
1WS3;
1WS2;
5FRC;
4PR8;
4POE;
4OQC;
4OP9;
4OP6;
4N9V;
4N9S;
4N9M;
4N3M;
4FSK;
4D19;
4D17;
4D13;
4D12;
4CW6;
4CW3;
4CW2;
4CW0;
3PLM;
3PLJ;
3PLI;
3PLH;
3PLG;
3PLE;
3PKU;
3PKT;
3PKS;
3PKL;
3PKK;
3PKH;
3PKG;
3PKF;
3PK8;
3PK6;
3PK5;
3PK4;
3PK3;
3P9O;
3P9F;
3OBP;
3LD4;
3LBG;
3L9G;
3L8W;
3GKO;
3F2M;
3CKU;
3CKS;
3BK8;
3BJP;
2ZKB;
2ZKA;
2PES;
2ICQ;
2IC0;
2IBA;
2FXL;
2FUB;
1XT4;
1WRR;
1R51;
1R4U;
1R4S;
2YZE;
2YZD;
2YZC;
2YZB;
5YJA;
5YJ2;
5Y52;
5AYJ;
4XFP;
3WLV;
1J2G;
5Z2B;
5Z2A;
5Z29;
5Z27;
5Y2P;
4PUV;
4MB8;
3PJK;
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References
External Links
| UniProtKB Enzyme Link: | UniProtKB 1.7.3.3 |
| BRENDA Enzyme Link: | BRENDA 1.7.3.3 |
| KEGG Enzyme Link: | KEGG1.7.3.3 |
| BioCyc Enzyme Link: | BioCyc 1.7.3.3 |
| ExPASy Enzyme Link: | ExPASy1.7.3.3 |
| EC2PDB Enzyme Link: | EC2PDB 1.7.3.3 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.7.3.3 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.7.3.3 |
| IntEnz Enzyme Link: | IntEnz 1.7.3.3 |
| MEDLINE Enzyme Link: | MEDLINE 1.7.3.3 |
| RHEA:21368 | H2O + O2 + urate = 5-hydroxyisourate + H2O2 |
| RULE(radius=1) | [*:1]=[c;H0;+0:2]1:[nH;+0:3]:[c;H0;+0:4]2:[nH;+0:5]:[c;H0;+0:6](=[*:7]):[nH;+0:8]:[c;H0;+0:9]:2:[c;H0;+0:10](=[*:11]):[nH;+0:12]:1.[O;H0;+0:13]=[O;H0;+0:14].[OH2;+0:15]>>[*:1]=[C;H0;+0:2]1-[N;H0;+0:3]=[C;H0;+0:4]2-[NH;+0:5]-[C;H0;+0:6](=[*:7])-[NH;+0:8]-[C;H0;+0:9]-2(-[OH;+0:15])-[C;H0;+0:10](=[*:11])-[NH;+0:12]-1.[OH;+0:13]-[OH;+0:14] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Spectroscopic characterization of intermediates in the urate oxidase reaction. | Kahn K, Tipton PA | 1998 Aug 18 | 9709003 |
| The all2 gene is required for the induction of the purine deamination pathway in Schizosaccharomyces pombe. | Fluri R, Kinghorn JR | 1985 Mar | 4020341 |
| The role of sex chromosomes in black fly evolution. | Feraday RM, Leonhardt KG, Brockhouse CL | 1989 Aug | 2680763 |
| Structural analysis of urate oxidase in complex with its natural substrate inhibited by cyanide: mechanistic implications. | Gabison L, Prangé T, Colloc'h N, El Hajji M, Castro B, Chiadmi M | 2008 Jul 20 | 18638417 |
| Oxygen pressurized X-ray crystallography: probing the dioxygen binding site in cofactorless urate oxidase and implications for its catalytic mechanism. | Colloc'h N, Gabison L, Monard G, Altarsha M, Chiadmi M, Marassio G, Sopkova-de Oliveira Santos J, El Hajji M, Castro B, Abraini JH, Prangé T | 2008 Sep | 18375516 |
| Urate oxidase from the rust Puccinia recondita is a heterotetramer with two different-sized monomers. | Aguilar M, Montalbini P, Pineda M | 2002 Apr | 11910495 |