EC number:1.8.1.16

Enzyme

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EC Tree
     1. Oxidoreductases
        1.8 Acting on a sulfur group of donors
            1.8.1 With NAD+ or NADP+ as acceptor
ID:1.8.1.16
Description:Glutathione amide reductase.
Alternative Name: GAR.
Prosite: PDOC00073;
PDB:
PDBScop
Cath: 3.30.390.30; 3.50.50.60;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.8.1.16
BRENDA Enzyme Link: BRENDA 1.8.1.16
KEGG Enzyme Link: KEGG1.8.1.16
BioCyc Enzyme Link: BioCyc 1.8.1.16
ExPASy Enzyme Link: ExPASy1.8.1.16
EC2PDB Enzyme Link: EC2PDB 1.8.1.16
ExplorEnz Enzyme Link: ExplorEnz 1.8.1.16
PRIAM enzyme-specific profiles Link: PRIAM 1.8.1.16
IntEnz Enzyme Link: IntEnz 1.8.1.16
MEDLINE Enzyme Link: MEDLINE 1.8.1.16

EC number:1.8.1.16

MSA:

1.8.1.16;
Phylogenetic Tree:

1.8.1.16;
Uniprot:
M-CSA:
RHEA:27433 2 glutathione amide + NAD(+) = glutathione amide disulfide + H(+) + NADH
RULE(radius=1) [*:1]-[SH;+0:2].[*:3]-[SH;+0:4].[*:5]-[n+;H0:6]1:[cH;+0:7]:[cH;+0:8]:[cH;+0:9]:[c;H0;+0:10](-[*:11]):[cH;+0:12]:1>>[*:5]-[N;H0;+0:6]1-[CH;+0:7]=[CH;+0:8]-[CH2;+0:9]-[C;H0;+0:10](-[*:11])=[CH;+0:12]-1.[*:1]-[S;H0;+0:2]-[S;H0;+0:4]-[*:3]
Reaction
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References

TitleAuthorsDatePubMed ID
Crystallization and preliminary X-ray crystallographic analysis of glutathione amide reductase from Chromatium gracile.Vergauwen B, Van Petegem F, Remaut H, Pauwels F, Van Beeumen JJ2002 Feb11807270
Characterization of glutathione amide reductase from Chromatium gracile. Identification of a novel thiol peroxidase (Prx/Grx) fueled by glutathione amide redox cycling.Vergauwen B, Pauwels F, Jacquemotte F, Meyer TE, Cusanovich MA, Bartsch RG, Van Beeumen JJ2001 Jun 1511399772