EC number:1.8.4.4

Enzyme

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EC Tree
     1. Oxidoreductases
        1.8 Acting on a sulfur group of donors
            1.8.4 With a disulfide as acceptor
ID:1.8.4.4
Description:Glutathione--cystine transhydrogenase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 1.8.4.4
BRENDA Enzyme Link: BRENDA 1.8.4.4
KEGG Enzyme Link: KEGG1.8.4.4
BioCyc Enzyme Link: BioCyc 1.8.4.4
ExPASy Enzyme Link: ExPASy1.8.4.4
EC2PDB Enzyme Link: EC2PDB 1.8.4.4
ExplorEnz Enzyme Link: ExplorEnz 1.8.4.4
PRIAM enzyme-specific profiles Link: PRIAM 1.8.4.4
IntEnz Enzyme Link: IntEnz 1.8.4.4
MEDLINE Enzyme Link: MEDLINE 1.8.4.4

EC number:1.8.4.4

MSA:

1.8.4.4;
Phylogenetic Tree:

1.8.4.4;
Uniprot:
M-CSA:
RHEA:12613 2 glutathione + L-cystine = glutathione disulfide + 2 L-cysteine
RULE(radius=1) [*:1]-[S;H0;+0:2]-[S;H0;+0:3]-[*:4].[*:5]-[SH;+0:6].[*:7]-[SH;+0:8]>>[*:5]-[S;H0;+0:6]-[S;H0;+0:8]-[*:7].[*:1]-[SH;+0:2].[*:4]-[SH;+0:3]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
A thiol-disulfide transhydrogenase from yeast.Nagai S, Black S1968 Apr 255646485