EC number:1.8.5.8
Enzyme
Download| EC Tree |
| 1. Oxidoreductases |
| 1.8 Acting on a sulfur group of donors |
| 1.8.5 With a quinone or similar compound as acceptor |
| ID: | 1.8.5.8 |
|---|---|
| Description: | Eukaryotic sulfide quinone oxidoreductase. |
| Alternative Name: |
SQOR. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 1.8.5.8 |
| BRENDA Enzyme Link: | BRENDA 1.8.5.8 |
| KEGG Enzyme Link: | KEGG1.8.5.8 |
| BioCyc Enzyme Link: | BioCyc 1.8.5.8 |
| ExPASy Enzyme Link: | ExPASy1.8.5.8 |
| EC2PDB Enzyme Link: | EC2PDB 1.8.5.8 |
| ExplorEnz Enzyme Link: | ExplorEnz 1.8.5.8 |
| PRIAM enzyme-specific profiles Link: | PRIAM 1.8.5.8 |
| IntEnz Enzyme Link: | IntEnz 1.8.5.8 |
| MEDLINE Enzyme Link: | MEDLINE 1.8.5.8 |
| RHEA:55156 | a quinone + glutathione + H(+) + hydrogen sulfide = a quinol + S-sulfanylglutathione |
| RULE(radius=1) | [*:1]-[C;H0;+0:2]1=[C;H0;+0:3](-[*:4])-[C;H0;+0:5](=[O;H0;+0:6])-[C;H0;+0:7](-[*:8])=[C;H0;+0:9](-[*:10])-[C;H0;+0:11]-1=[O;H0;+0:12].[*:13]-[SH;+0:14].[H+;H0:15].[SH2;+0:16]>>[*:13]-[S;H0;+0:14]-[SH;+0:16].[*:1]-[c;H0;+0:2]1:[c;H0;+0:3](-[*:4]):[c;H0;+0:5](-[OH;+0:6]):[c;H0;+0:7](-[*:8]):[c;H0;+0:9](-[*:10]):[c;H0;+0:11]:1-[OH;+0:12] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Organization of the human mitochondrial hydrogen sulfide oxidation pathway. | Libiad M, Yadav PK, Vitvitsky V, Martinov M, Banerjee R | 2014 Nov 7 | 25225291 |
| Human sulfide:quinone oxidoreductase catalyzes the first step in hydrogen sulfide metabolism and produces a sulfane sulfur metabolite. | Jackson MR, Melideo SL, Jorns MS | 2012 Aug 28 | 22852582 |
| Three enzymatic activities catalyze the oxidation of sulfide to thiosulfate in mammalian and invertebrate mitochondria. | Hildebrandt TM, Grieshaber MK | 2008 Jul | 18494801 |
| A fission yeast gene for mitochondrial sulfide oxidation. | Vande Weghe JG, Ow DW | 1999 May 7 | 10224084 |