Enzyme

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EC Tree
     1. Oxidoreductases
        1.8 Acting on a sulfur group of donors
            1.8.98 With other, known, physiological acceptors
ID:1.8.98.1
Description:Dihydromethanophenazine:CoB--CoM heterodisulfide reductase.
Alternative Name: Heterodisulfide reductase.
CoB--CoM heterodisulfide reductase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 1.8.98.1
BRENDA Enzyme Link: BRENDA 1.8.98.1
KEGG Enzyme Link: KEGG1.8.98.1
BioCyc Enzyme Link: BioCyc 1.8.98.1
ExPASy Enzyme Link: ExPASy1.8.98.1
EC2PDB Enzyme Link: EC2PDB 1.8.98.1
ExplorEnz Enzyme Link: ExplorEnz 1.8.98.1
PRIAM enzyme-specific profiles Link: PRIAM 1.8.98.1
IntEnz Enzyme Link: IntEnz 1.8.98.1
MEDLINE Enzyme Link: MEDLINE 1.8.98.1
MSA:

1.8.98.1;

Phylogenetic Tree:

1.8.98.1;

Uniprot:
M-CSA:
RHEA:18085 coenzyme B + coenzyme M + methanophenazine = coenzyme M-coenzyme B heterodisulfide + dihydromethanophenazine
RULE(radius=1) [*:1]-[SH;+0:2].[*:3]-[SH;+0:4].[*:5]1:[*:6]:[n;H0;+0:7]:[*:8]:[*:9]:[n;H0;+0:10]:1>>[*:1]-[S;H0;+0:2]-[S;H0;+0:4]-[*:3].[*:5]1:[*:6]-[NH;+0:7]-[*:8]:[*:9]-[NH;+0:10]-1
Reaction
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References

TitleAuthorsDatePubMed ID
Purification and properties of the heme- and iron-sulfur-containing heterodisulfide reductase from Methanosarcina thermophila.Simianu M, Murakami E, Brewer JM, Ragsdale SW1998 Jul 149665708
Isolation and characterization of methanophenazine and function of phenazines in membrane-bound electron transport of Methanosarcina mazei Gö1.Abken HJ, Tietze M, Brodersen J, Bäumer S, Beifuss U, Deppenmeier U1998 Apr9555882
Purification and properties of heterodisulfide reductase from Methanobacterium thermoautotrophicum (strain Marburg).Hedderich R, Berkessel A, Thauer RK1990 Oct 52121478
Characterization of the intramolecular electron transfer pathway from 2-hydroxyphenazine to the heterodisulfide reductase from Methanosarcina thermophila.Murakami E, Deppenmeier U, Ragsdale SW2001 Jan 2611034998