EC number:2.1.1.102

Enzyme

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     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.1 Methyltransferases
ID:2.1.1.102
Description:Demethylmacrocin O-methyltransferase.
Alternative Name: DMOMT.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.1.102
BRENDA Enzyme Link: BRENDA 2.1.1.102
KEGG Enzyme Link: KEGG2.1.1.102
BioCyc Enzyme Link: BioCyc 2.1.1.102
ExPASy Enzyme Link: ExPASy2.1.1.102
EC2PDB Enzyme Link: EC2PDB 2.1.1.102
ExplorEnz Enzyme Link: ExplorEnz 2.1.1.102
PRIAM enzyme-specific profiles Link: PRIAM 2.1.1.102
IntEnz Enzyme Link: IntEnz 2.1.1.102
MEDLINE Enzyme Link: MEDLINE 2.1.1.102

EC number:2.1.1.102

MSA:

2.1.1.102;
Phylogenetic Tree:

2.1.1.102;
Uniprot:
M-CSA:
RHEA:17573 demethylmacrocin + S-adenosyl-L-methionine = H(+) + macrocin + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]-[S+;H0:4](-[*:5])-[CH3;+0:6]>>[*:1]-[O;H0;+0:2]-[CH3;+0:6].[*:3]-[S;H0;+0:4]-[*:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Two distinctive O-methyltransferases catalyzing penultimate and terminal reactions of macrolide antibiotic (tylosin) biosynthesis. Substrate specificity, enzyme inhibition, and kinetic mechanism.Kreuzman AJ, Turner JR, Yeh WK1988 Oct 253170602