EC number:2.1.1.103

Enzyme

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     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.1 Methyltransferases
ID:2.1.1.103
Description:Phosphoethanolamine N-methyltransferase.
Cath: 3.40.50.150;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.1.103
BRENDA Enzyme Link: BRENDA 2.1.1.103
KEGG Enzyme Link: KEGG2.1.1.103
BioCyc Enzyme Link: BioCyc 2.1.1.103
ExPASy Enzyme Link: ExPASy2.1.1.103
EC2PDB Enzyme Link: EC2PDB 2.1.1.103
ExplorEnz Enzyme Link: ExplorEnz 2.1.1.103
PRIAM enzyme-specific profiles Link: PRIAM 2.1.1.103
IntEnz Enzyme Link: IntEnz 2.1.1.103
MEDLINE Enzyme Link: MEDLINE 2.1.1.103

EC number:2.1.1.103

MSA:

2.1.1.103;
Phylogenetic Tree:

2.1.1.103;
Uniprot:
M-CSA:
RHEA:25325 N,N-dimethylethanolamine phosphate + S-adenosyl-L-methionine = H(+) + phosphocholine + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[N;H0;+0:2](-[*:3])-[*:4].[*:5]-[S+;H0:6](-[*:7])-[CH3;+0:8]>>[*:1]-[N+;H0:2](-[*:3])(-[*:4])-[CH3;+0:8].[*:5]-[S;H0;+0:6]-[*:7]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction
RHEA:25321 N-methylethanolamine phosphate + S-adenosyl-L-methionine = H(+) + N,N-dimethylethanolamine phosphate + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[NH;+0:2]-[*:3].[*:4]-[S+;H0:5](-[*:6])-[CH3;+0:7]>>[*:1]-[N;H0;+0:2](-[*:3])-[CH3;+0:7].[*:4]-[S;H0;+0:5]-[*:6]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction
RHEA:20365 phosphoethanolamine + S-adenosyl-L-methionine = H(+) + N-methylethanolamine phosphate + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[NH2;+0:2].[*:3]-[S+;H0:4](-[*:5])-[CH3;+0:6]>>[*:1]-[NH;+0:2]-[CH3;+0:6].[*:3]-[S;H0;+0:4]-[*:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Enzymes of phosphatidylcholine synthesis in lemna, soybean, and carrot.Datko AH, Mudd SH1988 Dec16666464
Phosphoethanolamine N-methyltransferase (PMT-1) catalyses the first reaction of a new pathway for phosphocholine biosynthesis in Caenorhabditis elegans.Brendza KM, Haakenson W, Cahoon RE, Hicks LM, Palavalli LH, Chiapelli BJ, McLaird M, McCarter JP, Williams DJ, Hresko MC, Jez JM2007 Jun 1517313371