EC number:2.1.1.110
| ID: | 2.1.1.110 |
|---|---|
| Description: | Sterigmatocystin 8-O-methyltransferase. |
| Alternative Name: |
Sterigmatocystin methyltransferase. Sterigmatocystin 7-O-methyltransferase. S-adenosyl-L-methionine:sterigmatocystin 7-O-methyltransferase. O-methyltransferase II. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.1.1.110 |
| BRENDA Enzyme Link: | BRENDA 2.1.1.110 |
| KEGG Enzyme Link: | KEGG2.1.1.110 |
| BioCyc Enzyme Link: | BioCyc 2.1.1.110 |
| ExPASy Enzyme Link: | ExPASy2.1.1.110 |
| EC2PDB Enzyme Link: | EC2PDB 2.1.1.110 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.1.1.110 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.1.1.110 |
| IntEnz Enzyme Link: | IntEnz 2.1.1.110 |
| MEDLINE Enzyme Link: | MEDLINE 2.1.1.110 |
EC number:2.1.1.110
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:35767 | dihydrosterigmatocystin + S-adenosyl-L-methionine = 8-O-methyldihydrosterigmatocystin + H(+) + S-adenosyl-L-homocysteine |
| RULE(radius=1) | [*:1]-[OH;+0:2].[*:3]-[S+;H0:4](-[*:5])-[CH3;+0:6]>>[*:1]-[O;H0;+0:2]-[CH3;+0:6].[*:3]-[S;H0;+0:4]-[*:5] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Identification of O-methylsterigmatocystin as an aflatoxin B1 and G1 precursor in Aspergillus parasiticus. | Bhatnagar D, McCormick SP, Lee LS, Hill RA | 1987 May | 3111363 |
| Cloning and characterization of a cDNA from Aspergillus parasiticus encoding an O-methyltransferase involved in aflatoxin biosynthesis. | Yu J, Cary JW, Bhatnagar D, Cleveland TE, Keller NP, Chu FS | 1993 Nov | 8285664 |
| Function of native OmtA in vivo and expression and distribution of this protein in colonies of Aspergillus parasiticus. | Lee LW, Chiou CH, Linz JE | 2002 Nov | 12406770 |
| RHEA:15561 | S-adenosyl-L-methionine + sterigmatocystin = 8-O-methylsterigmatocystin + H(+) + S-adenosyl-L-homocysteine |
| RULE(radius=1) | [*:1]-[OH;+0:2].[*:3]-[S+;H0:4](-[*:5])-[CH3;+0:6]>>[*:1]-[O;H0;+0:2]-[CH3;+0:6].[*:3]-[S;H0;+0:4]-[*:5] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Identification of O-methylsterigmatocystin as an aflatoxin B1 and G1 precursor in Aspergillus parasiticus. | Bhatnagar D, McCormick SP, Lee LS, Hill RA | 1987 May | 3111363 |
| Two distinct O-methyltransferases in aflatoxin biosynthesis. | Yabe K, Ando Y, Hashimoto J, Hamasaki T | 1989 Sep | 2802602 |