EC number:2.1.1.115

Enzyme

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     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.1 Methyltransferases
ID:2.1.1.115
Description:(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline N-methyltransferase.
Alternative Name: Norreticuline N-methyltransferase.
(RS)-tetrahydrobenzylisoquinoline N-methyltransferase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.1.115
BRENDA Enzyme Link: BRENDA 2.1.1.115
KEGG Enzyme Link: KEGG2.1.1.115
BioCyc Enzyme Link: BioCyc 2.1.1.115
ExPASy Enzyme Link: ExPASy2.1.1.115
EC2PDB Enzyme Link: EC2PDB 2.1.1.115
ExplorEnz Enzyme Link: ExplorEnz 2.1.1.115
PRIAM enzyme-specific profiles Link: PRIAM 2.1.1.115
IntEnz Enzyme Link: IntEnz 2.1.1.115
MEDLINE Enzyme Link: MEDLINE 2.1.1.115

EC number:2.1.1.115

MSA:

2.1.1.115;
Phylogenetic Tree:

2.1.1.115;
Uniprot:
M-CSA:
RHEA:13005 (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline + S-adenosyl-L-methionine = H(+) + N-methyl-(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[NH;+0:2]-[*:3].[*:4]-[S+;H0:5](-[*:6])-[CH3;+0:7]>>[*:1]-[N;H0;+0:2](-[*:3])-[CH3;+0:7].[*:4]-[S;H0;+0:5]-[*:6]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction