EC number:2.1.1.128

Enzyme

Download
EC Tree
     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.1 Methyltransferases
ID:2.1.1.128
Description:(RS)-norcoclaurine 6-O-methyltransferase.
Cath: 1.10.10.10; 3.40.50.150;

3D structure

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.
PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.1.128
BRENDA Enzyme Link: BRENDA 2.1.1.128
KEGG Enzyme Link: KEGG2.1.1.128
BioCyc Enzyme Link: BioCyc 2.1.1.128
ExPASy Enzyme Link: ExPASy2.1.1.128
EC2PDB Enzyme Link: EC2PDB 2.1.1.128
ExplorEnz Enzyme Link: ExplorEnz 2.1.1.128
PRIAM enzyme-specific profiles Link: PRIAM 2.1.1.128
IntEnz Enzyme Link: IntEnz 2.1.1.128
MEDLINE Enzyme Link: MEDLINE 2.1.1.128

EC number:2.1.1.128

MSA:

2.1.1.128;
Phylogenetic Tree:

2.1.1.128;
Uniprot:
M-CSA:
RHEA:31907 (S)-norcoclaurine + S-adenosyl-L-methionine = (S)-coclaurine + H(+) + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]-[S+;H0:4](-[*:5])-[CH3;+0:6]>>[*:1]-[O;H0;+0:2]-[CH3;+0:6].[*:3]-[S;H0;+0:4]-[*:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Purification and characterization of S-adenosyl-L-methionine: norcoclaurine 6-O-methyltransferase from cultured Coptis japonica cells.Sato F, Tsujita T, Katagiri Y, Yoshida S, Yamada Y1994 Oct 17925429
RHEA:19941 norcoclaurine + S-adenosyl-L-methionine = coclaurine + H(+) + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]-[S+;H0:4](-[*:5])-[CH3;+0:6]>>[*:1]-[O;H0;+0:2]-[CH3;+0:6].[*:3]-[S;H0;+0:4]-[*:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Partial Purification and Properties of S-Adenosylmethionine: (R), (S)-Norlaudanosoline-6-O-Methyltransferase from Argemone platyceras Cell Cultures.Rueffer M, Nagakura N, Zenk MH1983 Nov17405035
Purification and characterization of S-adenosyl-L-methionine: norcoclaurine 6-O-methyltransferase from cultured Coptis japonica cells.Sato F, Tsujita T, Katagiri Y, Yoshida S, Yamada Y1994 Oct 17925429