Enzyme

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     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.1 Methyltransferases
ID:2.1.1.133
Description:Precorrin-4 C(11)-methyltransferase.
Alternative Name: Precorrin-4 C11-methyltransferase.
Precorrin-3 methylase.
Cath: 3.30.950.10; 3.40.1010.10;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.1.133
BRENDA Enzyme Link: BRENDA 2.1.1.133
KEGG Enzyme Link: KEGG2.1.1.133
BioCyc Enzyme Link: BioCyc 2.1.1.133
ExPASy Enzyme Link: ExPASy2.1.1.133
EC2PDB Enzyme Link: EC2PDB 2.1.1.133
ExplorEnz Enzyme Link: ExplorEnz 2.1.1.133
PRIAM enzyme-specific profiles Link: PRIAM 2.1.1.133
IntEnz Enzyme Link: IntEnz 2.1.1.133
MEDLINE Enzyme Link: MEDLINE 2.1.1.133
MSA:

2.1.1.133;

Phylogenetic Tree:

2.1.1.133;

Uniprot:
M-CSA:
RHEA:22012 precorrin-4 + S-adenosyl-L-methionine = precorrin-5 + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[S+;H0:2](-[*:3])-[CH3;+0:4].[*:5]-[c;H0;+0:6]1:[c;H0;+0:7](-[*:8]):[c;H0;+0:9](-[*:10]):[nH;+0:11]:[c;H0;+0:12]:1-[*:13]>>[*:5]-[C;H0;+0:6]1=[C;H0;+0:7](-[*:8])-[C;H0;+0:9](-[*:10])(-[CH3;+0:4])-[N;H0;+0:11]=[C;H0;+0:12]-1-[*:13].[*:1]-[S;H0;+0:2]-[*:3]
Reaction
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References

TitleAuthorsDatePubMed ID
Characterization of the cobalamin (vitamin B12) biosynthetic genes of Salmonella typhimurium.Roth JR, Lawrence JG, Rubenfield M, Kieffer-Higgins S, Church GM1993 Jun8501034
Genetic and sequence analysis of an 8.7-kilobase Pseudomonas denitrificans fragment carrying eight genes involved in transformation of precorrin-2 to cobyrinic acid.Crouzet J, Cameron B, Cauchois L, Rigault S, Rouyez MC, Blanche F, Thibaut D, Debussche L1990 Oct2211521