EC number:2.1.1.150
| ID: | 2.1.1.150 |
|---|---|
| Description: | Isoflavone 7-O-methyltransferase. |
| Cath: | 1.10.10.10; 3.40.50.150; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.1.1.150 |
| BRENDA Enzyme Link: | BRENDA 2.1.1.150 |
| KEGG Enzyme Link: | KEGG2.1.1.150 |
| BioCyc Enzyme Link: | BioCyc 2.1.1.150 |
| ExPASy Enzyme Link: | ExPASy2.1.1.150 |
| EC2PDB Enzyme Link: | EC2PDB 2.1.1.150 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.1.1.150 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.1.1.150 |
| IntEnz Enzyme Link: | IntEnz 2.1.1.150 |
| MEDLINE Enzyme Link: | MEDLINE 2.1.1.150 |
EC number:2.1.1.150
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:17933 | a 7-hydroxyisoflavone + S-adenosyl-L-methionine = a 7-methoxyisoflavone + H(+) + S-adenosyl-L-homocysteine |
| RULE(radius=1) | [*:1]-[OH;+0:2].[*:3]-[S+;H0:4](-[*:5])-[CH3;+0:6]>>[*:1]-[O;H0;+0:2]-[CH3;+0:6].[*:3]-[S;H0;+0:4]-[*:5] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Stress responses in alfalfa (Medicago sativa L). XXII. cDNA cloning and characterization of an elicitor-inducible isoflavone 7-O-methyltransferase. | He XZ, Reddy JT, Dixon RA | 1998 Jan | 9484461 |
| Affinity chromatography, substrate/product specificity, and amino acid sequence analysis of an isoflavone O-methyltransferase from alfalfa (Medicago sativa L.). | He XZ, Dixon RA | 1996 Dec 1 | 8951042 |
| Elicitor-induced association of isoflavone O-methyltransferase with endomembranes prevents the formation and 7-O-methylation of daidzein during isoflavonoid phytoalexin biosynthesis. | Liu CJ, Dixon RA | 2001 Dec | 11752378 |
| Genetic manipulation of isoflavone 7-O-methyltransferase enhances biosynthesis of 4'-O-methylated isoflavonoid phytoalexins and disease resistance in alfalfa. | He XZ, Dixon RA | 2000 Sep | 11006341 |
| cDNA cloning and biochemical characterization of S-adenosyl-L-methionine: 2,7,4'-trihydroxyisoflavanone 4'-O-methyltransferase, a critical enzyme of the legume isoflavonoid phytoalexin pathway. | Akashi T, Sawada Y, Shimada N, Sakurai N, Aoki T, Ayabe S | 2003 Feb | 12610212 |
| Structures of two natural product methyltransferases reveal the basis for substrate specificity in plant O-methyltransferases. | Zubieta C, He XZ, Dixon RA, Noel JP | 2001 Mar | 11224575 |