EC number:2.1.1.152

Enzyme

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     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.1 Methyltransferases
ID:2.1.1.152
Description:Precorrin-6A synthase (deacetylating).
Alternative Name: Precorrin-6X synthase (deacetylating).
Cath: 3.30.950.10; 3.40.1010.10;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.1.152
BRENDA Enzyme Link: BRENDA 2.1.1.152
KEGG Enzyme Link: KEGG2.1.1.152
BioCyc Enzyme Link: BioCyc 2.1.1.152
ExPASy Enzyme Link: ExPASy2.1.1.152
EC2PDB Enzyme Link: EC2PDB 2.1.1.152
ExplorEnz Enzyme Link: ExplorEnz 2.1.1.152
PRIAM enzyme-specific profiles Link: PRIAM 2.1.1.152
IntEnz Enzyme Link: IntEnz 2.1.1.152
MEDLINE Enzyme Link: MEDLINE 2.1.1.152

EC number:2.1.1.152

MSA:

2.1.1.152;
Phylogenetic Tree:

2.1.1.152;
Uniprot:
M-CSA:
RHEA:18261 H2O + precorrin-5 + S-adenosyl-L-methionine = acetate + 2 H(+) + precorrin-6A + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[C;H0;+0:2](-[*:3])(-[*:4])-[C;H0;+0:5](=[*:6])-[*:7].[*:8]-[S+;H0:9](-[*:10])-[CH3;+0:11].[OH2;+0:12]>>[*:1]-[C;H0;+0:2](-[*:3])(-[*:4])-[CH3;+0:11].[*:8]-[S;H0;+0:9]-[*:10].[*:6]=[C;H0;+0:5](-[*:7])-[OH;+0:12]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Biosynthesis of the corrin macrocycle of coenzyme B12 in Pseudomonas denitrificans.Debussche L, Thibaut D, Cameron B, Crouzet J, Blanche F1993 Nov8226690
The biosynthesis of adenosylcobalamin (vitamin B12).Warren MJ, Raux E, Schubert HL, Escalante-Semerena JC2002 Aug12195810