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2. Transferases

2.1 Transferring one-carbon groups

2.1.1 Methyltransferases

ID:	2.1.1.154
Description:	Isoliquiritigenin 2'-O-methyltransferase.
Alternative Name:	CHMT. Chalcone OMT.
Cath:	1.10.10.10; 3.40.50.150;

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UniProtKB Enzyme Link:	UniProtKB 2.1.1.154
BRENDA Enzyme Link:	BRENDA 2.1.1.154
KEGG Enzyme Link:	KEGG2.1.1.154
BioCyc Enzyme Link:	BioCyc 2.1.1.154
ExPASy Enzyme Link:	ExPASy2.1.1.154
EC2PDB Enzyme Link:	EC2PDB 2.1.1.154
ExplorEnz Enzyme Link:	ExplorEnz 2.1.1.154
PRIAM enzyme-specific profiles Link:	PRIAM 2.1.1.154
IntEnz Enzyme Link:	IntEnz 2.1.1.154
MEDLINE Enzyme Link:	MEDLINE 2.1.1.154

RHEA:21608	isoliquiritigenin + S-adenosyl-L-methionine = 2'-O-methylisoliquiritigenin + S-adenosyl-L-homocysteine
RULE(radius=1)	[:1]-[OH;+0:2].[:3]-[S+;H0:4](-[:5])-[CH3;+0:6]>>[:1]-[O;H0;+0:2]-[CH3;+0:6].[:3]-[S;H0;+0:4]-[:5]
Reaction
Core-to-Core	No scaffolds atoms were exchanged as a result of the reaction

Title	Authors	Date	PubMed ID
Enzymic O-methylation of isoliquiritigenin and licodione in alfalfa and licorice cultures.	Ichimura M, Furuno T, Takahashi T, Dixon RA, Ayabe S	1997 Mar	9055445
Molecular characterization and expression of alfalfa isoliquiritigenin 2'-O-methyltransferase, an enzyme specifically involved in the biosynthesis of an inducer of Rhizobium meliloti nodulation genes.	Maxwell CA, Harrison MJ, Dixon RA	1993 Dec	8281189
Identification, purification, and characterization of S-adenosyl-L-methionine: isoliquiritigenin 2'-O-methyltransferase from alfalfa (Medicago sativa L.).	Maxwell CA, Edwards R, Dixon RA	1992 Feb 14	1731632
Structures of two natural product methyltransferases reveal the basis for substrate specificity in plant O-methyltransferases.	Zubieta C, He XZ, Dixon RA, Noel JP	2001 Mar	11224575