EC number:2.1.1.156
| ID: | 2.1.1.156 |
|---|---|
| Description: | Glycine/sarcosine N-methyltransferase. |
| Alternative Name: |
GSMT. GMT. Glycine-sarcosine methyltransferase. Glycine sarcosine N-methyltransferase. |
| Cath: | 3.40.605.10; 3.40.309.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.1.1.156 |
| BRENDA Enzyme Link: | BRENDA 2.1.1.156 |
| KEGG Enzyme Link: | KEGG2.1.1.156 |
| BioCyc Enzyme Link: | BioCyc 2.1.1.156 |
| ExPASy Enzyme Link: | ExPASy2.1.1.156 |
| EC2PDB Enzyme Link: | EC2PDB 2.1.1.156 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.1.1.156 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.1.1.156 |
| IntEnz Enzyme Link: | IntEnz 2.1.1.156 |
| MEDLINE Enzyme Link: | MEDLINE 2.1.1.156 |
EC number:2.1.1.156
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:32463 | glycine + 2 S-adenosyl-L-methionine = 2 H(+) + N,N-dimethylglycine + 2 S-adenosyl-L-homocysteine |
| RULE(radius=1) | [*:1]-[NH2;+0:2].[*:3]-[S+;H0:4](-[*:5])-[CH3;+0:6].[*:7]-[S+;H0:8](-[*:9])-[CH3;+0:10]>>[*:1]-[N;H0;+0:2](-[CH3;+0:10])-[CH3;+0:6].[*:3]-[S;H0;+0:4]-[*:5].[*:7]-[S;H0;+0:8]-[*:9] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Identification of glycine betaine as compatible solute in Synechococcus sp. WH8102 and characterization of its N-methyltransferase genes involved in betaine synthesis. | Lu WD, Chi ZM, Su CD | 2006 Dec | 17019606 |
| Isolation and functional characterization of N-methyltransferases that catalyze betaine synthesis from glycine in a halotolerant photosynthetic organism Aphanothece halophytica. | Waditee R, Tanaka Y, Aoki K, Hibino T, Jikuya H, Takano J, Takabe T, Takabe T | 2003 Feb 14 | 12466265 |
| Characterization of glycine sarcosine N-methyltransferase and sarcosine dimethylglycine N-methyltransferase. | Nyyssölä A, Reinikainen T, Leisola M | 2001 May | 11319079 |
| Extreme halophiles synthesize betaine from glycine by methylation. | Nyyssola A, Kerovuo J, Kaukinen P, von Weymarn N, Reinikainen T | 2000 Jul 21 | 10896953 |