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2. Transferases

2.1 Transferring one-carbon groups

2.1.1 Methyltransferases

ID:	2.1.1.157
Description:	Sarcosine/dimethylglycine N-methyltransferase.
Alternative Name:	SDMT. Sarcosine-dimethylglycine methyltransferase. Sarcosine dimethylglycine N-methyltransferase. ApDMT.
Cath:	3.40.605.10; 3.40.309.10;

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UniProtKB Enzyme Link:	UniProtKB 2.1.1.157
BRENDA Enzyme Link:	BRENDA 2.1.1.157
KEGG Enzyme Link:	KEGG2.1.1.157
BioCyc Enzyme Link:	BioCyc 2.1.1.157
ExPASy Enzyme Link:	ExPASy2.1.1.157
EC2PDB Enzyme Link:	EC2PDB 2.1.1.157
ExplorEnz Enzyme Link:	ExplorEnz 2.1.1.157
PRIAM enzyme-specific profiles Link:	PRIAM 2.1.1.157
IntEnz Enzyme Link:	IntEnz 2.1.1.157
MEDLINE Enzyme Link:	MEDLINE 2.1.1.157

RHEA:32467	2 S-adenosyl-L-methionine + sarcosine = betaine + 2 H(+) + 2 S-adenosyl-L-homocysteine
RULE(radius=1)	[:1]-[NH;+0:2]-[:3].[:4]-[S+;H0:5](-[:6])-[CH3;+0:7].[:8]-[S+;H0:9](-[:10])-[CH3;+0:11]>>[:1]-[N+;H0:2](-[:3])(-[CH3;+0:11])-[CH3;+0:7].[:4]-[S;H0;+0:5]-[:6].[:8]-[S;H0;+0:9]-[:10]
Reaction
Core-to-Core	No scaffolds atoms were exchanged as a result of the reaction

Title	Authors	Date	PubMed ID
Isolation and functional characterization of N-methyltransferases that catalyze betaine synthesis from glycine in a halotolerant photosynthetic organism Aphanothece halophytica.	Waditee R, Tanaka Y, Aoki K, Hibino T, Jikuya H, Takano J, Takabe T, Takabe T	2003 Feb 14	12466265
Characterization of glycine sarcosine N-methyltransferase and sarcosine dimethylglycine N-methyltransferase.	Nyyssölä A, Reinikainen T, Leisola M	2001 May	11319079
Extreme halophiles synthesize betaine from glycine by methylation.	Nyyssola A, Kerovuo J, Kaukinen P, von Weymarn N, Reinikainen T	2000 Jul 21	10896953