EC number:2.1.1.159
| ID: | 2.1.1.159 |
|---|---|
| Description: | Theobromine synthase. |
| Alternative Name: |
MXMT. Monomethylxanthine methyltransferase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.1.1.159 |
| BRENDA Enzyme Link: | BRENDA 2.1.1.159 |
| KEGG Enzyme Link: | KEGG2.1.1.159 |
| BioCyc Enzyme Link: | BioCyc 2.1.1.159 |
| ExPASy Enzyme Link: | ExPASy2.1.1.159 |
| EC2PDB Enzyme Link: | EC2PDB 2.1.1.159 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.1.1.159 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.1.1.159 |
| IntEnz Enzyme Link: | IntEnz 2.1.1.159 |
| MEDLINE Enzyme Link: | MEDLINE 2.1.1.159 |
EC number:2.1.1.159
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:24604 | 7-methylxanthine + S-adenosyl-L-methionine = H(+) + S-adenosyl-L-homocysteine + theobromine |
| RULE(radius=1) | [*:1]-[S+;H0:2](-[*:3])-[CH3;+0:4].[*:5]:[nH;+0:6]:[*:7]>>[*:1]-[S;H0;+0:2]-[*:3].[*:5]:[n;H0;+0:6](:[*:7])-[CH3;+0:4] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Substrate specificity of N-methyltransferase involved in purine alkaloids synthesis is dependent upon one amino acid residue of the enzyme. | Yoneyama N, Morimoto H, Ye CX, Ashihara H, Mizuno K, Kato M | 2006 Feb | 16333668 |
| Molecular cloning and functional characterization of three distinct N-methyltransferases involved in the caffeine biosynthetic pathway in coffee plants. | Uefuji H, Ogita S, Yamaguchi Y, Koizumi N, Sano H | 2003 May | 12746542 |
| Isolation of a new dual-functional caffeine synthase gene encoding an enzyme for the conversion of 7-methylxanthine to caffeine from coffee (Coffea arabica L.). | Mizuno K, Okuda A, Kato M, Yoneyama N, Tanaka H, Ashihara H, Fujimura T | 2003 Jan 16 | 12527364 |
| Caffeine synthase gene from tea leaves. | Kato M, Mizuno K, Crozier A, Fujimura T, Ashihara H | 2000 Aug 31 | 10984041 |
| 7-Methylxanthine methyltransferase of coffee plants. Gene isolation and enzymatic properties. | Ogawa M, Herai Y, Koizumi N, Kusano T, Sano H | 2001 Mar 16 | 11108716 |