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2. Transferases

2.1 Transferring one-carbon groups

2.1.1 Methyltransferases

ID:	2.1.1.161
Description:	Dimethylglycine N-methyltransferase.
Alternative Name:	DMT.

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UniProtKB Enzyme Link:	UniProtKB 2.1.1.161
BRENDA Enzyme Link:	BRENDA 2.1.1.161
KEGG Enzyme Link:	KEGG2.1.1.161
BioCyc Enzyme Link:	BioCyc 2.1.1.161
ExPASy Enzyme Link:	ExPASy2.1.1.161
EC2PDB Enzyme Link:	EC2PDB 2.1.1.161
ExplorEnz Enzyme Link:	ExplorEnz 2.1.1.161
PRIAM enzyme-specific profiles Link:	PRIAM 2.1.1.161
IntEnz Enzyme Link:	IntEnz 2.1.1.161
MEDLINE Enzyme Link:	MEDLINE 2.1.1.161

RHEA:10072	N,N-dimethylglycine + S-adenosyl-L-methionine = betaine + H(+) + S-adenosyl-L-homocysteine
RULE(radius=1)	[:1]-[N;H0;+0:2](-[:3])-[:4].[:5]-[S+;H0:6](-[:7])-[CH3;+0:8]>>[:1]-[N+;H0:2](-[:3])(-[:4])-[CH3;+0:8].[:5]-[S;H0;+0:6]-[:7]
Reaction
Core-to-Core	No scaffolds atoms were exchanged as a result of the reaction

Title	Authors	Date	PubMed ID
Identification of glycine betaine as compatible solute in Synechococcus sp. WH8102 and characterization of its N-methyltransferase genes involved in betaine synthesis.	Lu WD, Chi ZM, Su CD	2006 Dec	17019606
Isolation and functional characterization of N-methyltransferases that catalyze betaine synthesis from glycine in a halotolerant photosynthetic organism Aphanothece halophytica.	Waditee R, Tanaka Y, Aoki K, Hibino T, Jikuya H, Takano J, Takabe T, Takabe T	2003 Feb 14	12466265
Characterization of glycine sarcosine N-methyltransferase and sarcosine dimethylglycine N-methyltransferase.	Nyyssölä A, Reinikainen T, Leisola M	2001 May	11319079
Extreme halophiles synthesize betaine from glycine by methylation.	Nyyssola A, Kerovuo J, Kaukinen P, von Weymarn N, Reinikainen T	2000 Jul 21	10896953