EC number:2.1.1.162

Enzyme

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EC Tree
     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.1 Methyltransferases
ID:2.1.1.162
Description:Glycine/sarcosine/dimethylglycine N-methyltransferase.
Alternative Name: GSDMT.
Glycine sarcosine dimethylglycine N-methyltransferase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.1.162
BRENDA Enzyme Link: BRENDA 2.1.1.162
KEGG Enzyme Link: KEGG2.1.1.162
BioCyc Enzyme Link: BioCyc 2.1.1.162
ExPASy Enzyme Link: ExPASy2.1.1.162
EC2PDB Enzyme Link: EC2PDB 2.1.1.162
ExplorEnz Enzyme Link: ExplorEnz 2.1.1.162
PRIAM enzyme-specific profiles Link: PRIAM 2.1.1.162
IntEnz Enzyme Link: IntEnz 2.1.1.162
MEDLINE Enzyme Link: MEDLINE 2.1.1.162

EC number:2.1.1.162

MSA:

2.1.1.162;
Phylogenetic Tree:

2.1.1.162;
Uniprot:
M-CSA:
RHEA:32475 glycine + 3 S-adenosyl-L-methionine = betaine + 3 H(+) + 3 S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[NH2;+0:2].[*:3]-[S+;H0:4](-[*:5])-[CH3;+0:6].[*:7]-[S+;H0:8](-[*:9])-[CH3;+0:10].[*:11]-[S+;H0:12](-[*:13])-[CH3;+0:14]>>[*:1]-[N+;H0:2](-[CH3;+0:10])(-[CH3;+0:14])-[CH3;+0:6].[*:3]-[S;H0;+0:4]-[*:5].[*:7]-[S;H0;+0:8]-[*:9].[*:11]-[S;H0;+0:12]-[*:13]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Effects of substrate and potassium on the betaine-synthesizing enzyme glycine sarcosine dimethylglycine N-methyltransferase from a halophilic methanoarchaeon Methanohalophilus portucalensis.Lai MC, Wang CC, Chuang MJ, Wu YC, Lee YC2006 Dec17098399