EC number:2.1.1.164

Enzyme

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EC Tree
     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.1 Methyltransferases
ID:2.1.1.164
Description:Demethylrebeccamycin-D-glucose O-methyltransferase.
Cath: 3.40.50.150;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.1.164
BRENDA Enzyme Link: BRENDA 2.1.1.164
KEGG Enzyme Link: KEGG2.1.1.164
BioCyc Enzyme Link: BioCyc 2.1.1.164
ExPASy Enzyme Link: ExPASy2.1.1.164
EC2PDB Enzyme Link: EC2PDB 2.1.1.164
ExplorEnz Enzyme Link: ExplorEnz 2.1.1.164
PRIAM enzyme-specific profiles Link: PRIAM 2.1.1.164
IntEnz Enzyme Link: IntEnz 2.1.1.164
MEDLINE Enzyme Link: MEDLINE 2.1.1.164

EC number:2.1.1.164

MSA:

2.1.1.164;
Phylogenetic Tree:

2.1.1.164;
Uniprot:
M-CSA:
RHEA:27353 4'-demethylrebeccamycin + S-adenosyl-L-methionine = H(+) + rebeccamycin + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]-[S+;H0:4](-[*:5])-[CH3;+0:6]>>[*:1]-[O;H0;+0:2]-[CH3;+0:6].[*:3]-[S;H0;+0:4]-[*:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Structure and mechanism of the rebeccamycin sugar 4'-O-methyltransferase RebM.Singh S, McCoy JG, Zhang C, Bingman CA, Phillips GN Jr, Thorson JS2008 Aug 1518502766
RebG- and RebM-catalyzed indolocarbazole diversification.Zhang C, Albermann C, Fu X, Peters NR, Chisholm JD, Zhang G, Gilbert EJ, Wang PG, Van Vranken DL, Thorson JS2006 May16575939