Enzyme

Download
EC Tree
     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.1 Methyltransferases
ID:2.1.1.165
Description:Methyl halide transferase.
Alternative Name: Methyl chloride transferase.

3D structure

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.1.165
BRENDA Enzyme Link: BRENDA 2.1.1.165
KEGG Enzyme Link: KEGG2.1.1.165
BioCyc Enzyme Link: BioCyc 2.1.1.165
ExPASy Enzyme Link: ExPASy2.1.1.165
EC2PDB Enzyme Link: EC2PDB 2.1.1.165
ExplorEnz Enzyme Link: ExplorEnz 2.1.1.165
PRIAM enzyme-specific profiles Link: PRIAM 2.1.1.165
IntEnz Enzyme Link: IntEnz 2.1.1.165
MEDLINE Enzyme Link: MEDLINE 2.1.1.165
MSA:

2.1.1.165;

Phylogenetic Tree:

2.1.1.165;

Uniprot:
M-CSA:
RHEA:27365 bromide + S-adenosyl-L-methionine = bromomethane + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[S+;H0:2](-[*:3])-[CH3;+0:4].[Br-;H0:5]>>[*:1]-[S;H0;+0:2]-[*:3].[Br;H0;+0:5]-[CH3;+0:4]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Biochemical characterization of chloromethane emission from the wood-rotting fungus phellinus pomaceus Saxena D, Aouad S, Attieh J, Saini HS1998 Aug9687437
Purification and characterization of a novel methyltransferase responsible for biosynthesis of halomethanes and methanethiol in Brassica oleracea.Attieh JM, Hanson AD, Saini HS1995 Apr 217721844
Involvement of S-adenosylmethionine-dependent halide/thiol methyltransferase (HTMT) in methyl halide emissions from agricultural plants: isolation and characterization of an HTMT-coding gene from Raphanus sativus (daikon radish).Itoh N, Toda H, Matsuda M, Negishi T, Taniguchi T, Ohsawa N2009 Sep 119723322
Purification and characterization of a monohalomethane-producing enzyme S-adenosyl-L-methionine: halide ion methyltransferase from a marine microalga, Pavlova pinguis.Ohsawa N, Tsujita M, Morikawa S, Itoh N2001 Nov11791711
Expression of Batis maritima methyl chloride transferase in Escherichia coli.Ni X, Hager LP1999 Mar 3010097085

RHEA:27361 chloride + S-adenosyl-L-methionine = chloromethane + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[S+;H0:2](-[*:3])-[CH3;+0:4].[Cl-;H0:5]>>[*:1]-[S;H0;+0:2]-[*:3].[CH3;+0:4]-[Cl;H0;+0:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Biochemical characterization of chloromethane emission from the wood-rotting fungus phellinus pomaceus Saxena D, Aouad S, Attieh J, Saini HS1998 Aug9687437
Purification and characterization of a novel methyltransferase responsible for biosynthesis of halomethanes and methanethiol in Brassica oleracea.Attieh JM, Hanson AD, Saini HS1995 Apr 217721844
Involvement of S-adenosylmethionine-dependent halide/thiol methyltransferase (HTMT) in methyl halide emissions from agricultural plants: isolation and characterization of an HTMT-coding gene from Raphanus sativus (daikon radish).Itoh N, Toda H, Matsuda M, Negishi T, Taniguchi T, Ohsawa N2009 Sep 119723322
Purification and characterization of a monohalomethane-producing enzyme S-adenosyl-L-methionine: halide ion methyltransferase from a marine microalga, Pavlova pinguis.Ohsawa N, Tsujita M, Morikawa S, Itoh N2001 Nov11791711
Expression of Batis maritima methyl chloride transferase in Escherichia coli.Ni X, Hager LP1999 Mar 3010097085

RHEA:27357 iodide + S-adenosyl-L-methionine = iodomethane + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[S+;H0:2](-[*:3])-[CH3;+0:4].[I-;H0:5]>>[*:1]-[S;H0;+0:2]-[*:3].[CH3;+0:4]-[I;H0;+0:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Biochemical characterization of chloromethane emission from the wood-rotting fungus phellinus pomaceus Saxena D, Aouad S, Attieh J, Saini HS1998 Aug9687437
Purification and characterization of a novel methyltransferase responsible for biosynthesis of halomethanes and methanethiol in Brassica oleracea.Attieh JM, Hanson AD, Saini HS1995 Apr 217721844
Involvement of S-adenosylmethionine-dependent halide/thiol methyltransferase (HTMT) in methyl halide emissions from agricultural plants: isolation and characterization of an HTMT-coding gene from Raphanus sativus (daikon radish).Itoh N, Toda H, Matsuda M, Negishi T, Taniguchi T, Ohsawa N2009 Sep 119723322
Purification and characterization of a monohalomethane-producing enzyme S-adenosyl-L-methionine: halide ion methyltransferase from a marine microalga, Pavlova pinguis.Ohsawa N, Tsujita M, Morikawa S, Itoh N2001 Nov11791711
Expression of Batis maritima methyl chloride transferase in Escherichia coli.Ni X, Hager LP1999 Mar 3010097085