EC number:2.1.1.166

Enzyme

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     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.1 Methyltransferases
ID:2.1.1.166
Description:23S rRNA (uridine(2552)-2'-O)-methyltransferase.
Alternative Name: Um2552 methyltransferase.
Um(2552) 23S ribosomal RNA methyltransferase.
FTSJ.
Cath: 3.40.50.150;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.1.166
BRENDA Enzyme Link: BRENDA 2.1.1.166
KEGG Enzyme Link: KEGG2.1.1.166
BioCyc Enzyme Link: BioCyc 2.1.1.166
ExPASy Enzyme Link: ExPASy2.1.1.166
EC2PDB Enzyme Link: EC2PDB 2.1.1.166
ExplorEnz Enzyme Link: ExplorEnz 2.1.1.166
PRIAM enzyme-specific profiles Link: PRIAM 2.1.1.166
IntEnz Enzyme Link: IntEnz 2.1.1.166
MEDLINE Enzyme Link: MEDLINE 2.1.1.166

EC number:2.1.1.166

MSA:

2.1.1.166;
Phylogenetic Tree:

2.1.1.166;
Uniprot:
M-CSA:
RHEA:42720 S-adenosyl-L-methionine + uridine(2552) in 23S rRNA = 2'-O-methyluridine(2552) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]-[S+;H0:4](-[*:5])-[CH3;+0:6]>>[*:1]-[O;H0;+0:2]-[CH3;+0:6].[*:3]-[S;H0;+0:4]-[*:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Substrate binding analysis of the 23S rRNA methyltransferase RrmJ.Hager J, Staker BL, Jakob U2004 Oct15375145
The FtsJ/RrmJ heat shock protein of Escherichia coli is a 23 S ribosomal RNA methyltransferase.Caldas T, Binet E, Bouloc P, Costa A, Desgres J, Richarme G2000 Jun 210748051