EC number:2.1.1.170

Enzyme

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     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.1 Methyltransferases
ID:2.1.1.170
Description:16S rRNA (guanine(527)-N(7))-methyltransferase.
Cath: 3.40.50.150;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.1.170
BRENDA Enzyme Link: BRENDA 2.1.1.170
KEGG Enzyme Link: KEGG2.1.1.170
BioCyc Enzyme Link: BioCyc 2.1.1.170
ExPASy Enzyme Link: ExPASy2.1.1.170
EC2PDB Enzyme Link: EC2PDB 2.1.1.170
ExplorEnz Enzyme Link: ExplorEnz 2.1.1.170
PRIAM enzyme-specific profiles Link: PRIAM 2.1.1.170
IntEnz Enzyme Link: IntEnz 2.1.1.170
MEDLINE Enzyme Link: MEDLINE 2.1.1.170

EC number:2.1.1.170

MSA:

2.1.1.170;
Phylogenetic Tree:

2.1.1.170;
Uniprot:
M-CSA:
RHEA:42732 guanosine(527) in 16S rRNA + S-adenosyl-L-methionine = N(7)-methylguanosine(527) in 16S rRNA + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[S+;H0:2](-[*:3])-[CH3;+0:4].[*:5]:[n;H0;+0:6]:[*:7]>>[*:1]-[S;H0;+0:2]-[*:3].[*:5]:[n+;H0:6](:[*:7])-[CH3;+0:4]
Reaction
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References

TitleAuthorsDatePubMed ID
Loss of a conserved 7-methylguanosine modification in 16S rRNA confers low-level streptomycin resistance in bacteria.Okamoto S, Tamaru A, Nakajima C, Nishimura K, Tanaka Y, Tokuyama S, Suzuki Y, Ochi K2007 Feb17238915
Crystal structure of the Escherichia coli glucose-inhibited division protein B (GidB) reveals a methyltransferase fold.Romanowski MJ, Bonanno JB, Burley SK2002 Jun 112001236