EC number:2.1.1.173

Enzyme

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     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.1 Methyltransferases
ID:2.1.1.173
Description:23S rRNA (guanine(2445)-N(2))-methyltransferase.
Cath: 3.30.2130.30; 3.30.750.80; 3.40.50.150;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.1.173
BRENDA Enzyme Link: BRENDA 2.1.1.173
KEGG Enzyme Link: KEGG2.1.1.173
BioCyc Enzyme Link: BioCyc 2.1.1.173
ExPASy Enzyme Link: ExPASy2.1.1.173
EC2PDB Enzyme Link: EC2PDB 2.1.1.173
ExplorEnz Enzyme Link: ExplorEnz 2.1.1.173
PRIAM enzyme-specific profiles Link: PRIAM 2.1.1.173
IntEnz Enzyme Link: IntEnz 2.1.1.173
MEDLINE Enzyme Link: MEDLINE 2.1.1.173

EC number:2.1.1.173

MSA:

2.1.1.173;
Phylogenetic Tree:

2.1.1.173;
Uniprot:
M-CSA:
RHEA:42740 guanosine(2445) in 23S rRNA + S-adenosyl-L-methionine = H(+) + N(2)-methylguanosine(2445) in 23S rRNA + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[NH2;+0:2].[*:3]-[S+;H0:4](-[*:5])-[CH3;+0:6]>>[*:1]-[NH;+0:2]-[CH3;+0:6].[*:3]-[S;H0;+0:4]-[*:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Identification of Escherichia coli m2G methyltransferases: I. the ycbY gene encodes a methyltransferase specific for G2445 of the 23 S rRNA.Lesnyak DV, Sergiev PV, Bogdanov AA, Dontsova OA2006 Nov 1717010378