EC number:2.1.1.177

Enzyme

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     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.1 Methyltransferases
ID:2.1.1.177
Description:23S rRNA (pseudouridine(1915)-N(3))-methyltransferase.
Alternative Name: rRNA large subunit methyltransferase H.
Psi(1915)-specific methyltransferase.
Pseudouridine methyltransferase.
Cath: 3.40.1280.10;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.1.177
BRENDA Enzyme Link: BRENDA 2.1.1.177
KEGG Enzyme Link: KEGG2.1.1.177
BioCyc Enzyme Link: BioCyc 2.1.1.177
ExPASy Enzyme Link: ExPASy2.1.1.177
EC2PDB Enzyme Link: EC2PDB 2.1.1.177
ExplorEnz Enzyme Link: ExplorEnz 2.1.1.177
PRIAM enzyme-specific profiles Link: PRIAM 2.1.1.177
IntEnz Enzyme Link: IntEnz 2.1.1.177
MEDLINE Enzyme Link: MEDLINE 2.1.1.177

EC number:2.1.1.177

MSA:

2.1.1.177;
Phylogenetic Tree:

2.1.1.177;
Uniprot:
M-CSA:
RHEA:42752 pseudouridine(1915) in 23S rRNA + S-adenosyl-L-methionine = H(+) + N(3)-methylpseudouridine(1915) in 23S rRNA + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[S+;H0:2](-[*:3])-[CH3;+0:4].[*:5]:[nH;+0:6]:[*:7]>>[*:1]-[S;H0;+0:2]-[*:3].[*:5]:[n;H0;+0:6](:[*:7])-[CH3;+0:4]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Identification of pseudouridine methyltransferase in Escherichia coli.Ero R, Peil L, Liiv A, Remme J2008 Oct18755836
YbeA is the m3Psi methyltransferase RlmH that targets nucleotide 1915 in 23S rRNA.Purta E, Kaminska KH, Kasprzak JM, Bujnicki JM, Douthwaite S2008 Oct18755835