EC number:2.1.1.181

Enzyme

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     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.1 Methyltransferases
ID:2.1.1.181
Description:23S rRNA (adenine(1618)-N(6))-methyltransferase.
Alternative Name: rRNA large subunit methyltransferase F.
Prosite: PDOC00871;
PDB:
PDBScop
3R9X 8089830; 8089831; 8089832; 8089833; 8073145; 8073146; 8090719; 8090720;
3FYC 8089263; 8089264; 8090723; 8090724; 8089263; 8089264; 8090723; 8090724;
3GRY 8089263; 8089264; 8090723; 8090724;
3GRV 8089263; 8089264; 8090723; 8090724;
3GRU 8089263; 8089264; 8090723; 8090724;
 » show all

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.1.181
BRENDA Enzyme Link: BRENDA 2.1.1.181
KEGG Enzyme Link: KEGG2.1.1.181
BioCyc Enzyme Link: BioCyc 2.1.1.181
ExPASy Enzyme Link: ExPASy2.1.1.181
EC2PDB Enzyme Link: EC2PDB 2.1.1.181
ExplorEnz Enzyme Link: ExplorEnz 2.1.1.181
PRIAM enzyme-specific profiles Link: PRIAM 2.1.1.181
IntEnz Enzyme Link: IntEnz 2.1.1.181
MEDLINE Enzyme Link: MEDLINE 2.1.1.181

EC number:2.1.1.181

MSA:

2.1.1.181;
Phylogenetic Tree:

2.1.1.181;
Uniprot:
M-CSA:
RHEA:16497 adenosine(1618) in 23S rRNA + S-adenosyl-L-methionine = H(+) + N(6)-methyladenosine(1618) in 23S rRNA + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[NH2;+0:2].[*:3]-[S+;H0:4](-[*:5])-[CH3;+0:6]>>[*:1]-[NH;+0:2]-[CH3;+0:6].[*:3]-[S;H0;+0:4]-[*:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
The ybiN gene of Escherichia coli encodes adenine-N6 methyltransferase specific for modification of A1618 of 23 S ribosomal RNA, a methylated residue located close to the ribosomal exit tunnel.Sergiev PV, Serebryakova MV, Bogdanov AA, Dontsova OA2008 Jan 418021804