EC number:2.1.1.182

Enzyme

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     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.1 Methyltransferases
ID:2.1.1.182
Description:16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase.
Cath: 1.10.8.10; 1.10.8.100; 3.40.50.150;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.1.182
BRENDA Enzyme Link: BRENDA 2.1.1.182
KEGG Enzyme Link: KEGG2.1.1.182
BioCyc Enzyme Link: BioCyc 2.1.1.182
ExPASy Enzyme Link: ExPASy2.1.1.182
EC2PDB Enzyme Link: EC2PDB 2.1.1.182
ExplorEnz Enzyme Link: ExplorEnz 2.1.1.182
PRIAM enzyme-specific profiles Link: PRIAM 2.1.1.182
IntEnz Enzyme Link: IntEnz 2.1.1.182
MEDLINE Enzyme Link: MEDLINE 2.1.1.182

EC number:2.1.1.182

MSA:

2.1.1.182;
Phylogenetic Tree:

2.1.1.182;
Uniprot:
M-CSA:
RHEA:19609 adenosine(1518)/adenosine(1519) in 16S rRNA + 4 S-adenosyl-L-methionine = 4 H(+) + N(6)-dimethyladenosine(1518)/N(6)-dimethyladenosine(1519) in 16S rRNA + 4 S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[NH;+0:2]-[*:3].[*:4]-[S+;H0:5](-[*:6])-[CH3;+0:7]>>[*:1]-[N;H0;+0:2](-[*:3])-[CH3;+0:7].[*:4]-[S;H0;+0:5]-[*:6]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Methylation of the conserved A1518-A1519 in Escherichia coli 16S ribosomal RNA by the ksgA methyltransferase is influenced by methylations around the similarly conserved U1512.G1523 base pair in the 3' terminal hairpin.Formenoy LJ, Cunningham PR, Nurse K, Pleij CW, Ofengand J19947538324
Crystal structure of KsgA, a universally conserved rRNA adenine dimethyltransferase in Escherichia coli.O'Farrell HC, Scarsdale JN, Rife JP2004 May 2815136037