EC number:2.1.1.183
| ID: | 2.1.1.183 |
|---|---|
| Description: | 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase. |
| Cath: | 1.10.8.480; 3.40.50.150; |
3D structure
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.References
External Links
| UniProtKB Enzyme Link: | UniProtKB 2.1.1.183 |
| BRENDA Enzyme Link: | BRENDA 2.1.1.183 |
| KEGG Enzyme Link: | KEGG2.1.1.183 |
| BioCyc Enzyme Link: | BioCyc 2.1.1.183 |
| ExPASy Enzyme Link: | ExPASy2.1.1.183 |
| EC2PDB Enzyme Link: | EC2PDB 2.1.1.183 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.1.1.183 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.1.1.183 |
| IntEnz Enzyme Link: | IntEnz 2.1.1.183 |
| MEDLINE Enzyme Link: | MEDLINE 2.1.1.183 |
EC number:2.1.1.183
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:42780 | adenosine(1779)/adenosine(1780) in 18S rRNA + 4 S-adenosyl-L-methionine = 4 H(+) + N(6)-dimethyladenosine(1779)/N(6)-dimethyladenosine(1780) in 18S rRNA + 4 S-adenosyl-L-homocysteine |
| RULE(radius=1) | [*:1]-[NH;+0:2]-[*:3].[*:4]-[S+;H0:5](-[*:6])-[CH3;+0:7]>>[*:1]-[N;H0;+0:2](-[*:3])-[CH3;+0:7].[*:4]-[S;H0;+0:5]-[*:6] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| The DIM1 gene responsible for the conserved m6(2)Am6(2)A dimethylation in the 3'-terminal loop of 18 S rRNA is essential in yeast. | Lafontaine D, Delcour J, Glasser AL, Desgrès J, Vandenhaute J | 1994 Aug 19 | 8064863 |
| Structural and functional divergence within the Dim1/KsgA family of rRNA methyltransferases. | Pulicherla N, Pogorzala LA, Xu Z, O Farrell HC, Musayev FN, Scarsdale JN, Sia EA, Culver GM, Rife JP | 2009 Sep 4 | 19520088 |