EC number:2.1.1.186

Enzyme

Download
EC Tree
     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.1 Methyltransferases
ID:2.1.1.186
Description:23S rRNA (cytidine(2498)-2'-O)-methyltransferase.
Cath: 3.30.2300.20; 3.30.70.2810; 3.40.50.150;

3D structure

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.
PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.1.186
BRENDA Enzyme Link: BRENDA 2.1.1.186
KEGG Enzyme Link: KEGG2.1.1.186
BioCyc Enzyme Link: BioCyc 2.1.1.186
ExPASy Enzyme Link: ExPASy2.1.1.186
EC2PDB Enzyme Link: EC2PDB 2.1.1.186
ExplorEnz Enzyme Link: ExplorEnz 2.1.1.186
PRIAM enzyme-specific profiles Link: PRIAM 2.1.1.186
IntEnz Enzyme Link: IntEnz 2.1.1.186
MEDLINE Enzyme Link: MEDLINE 2.1.1.186

EC number:2.1.1.186

MSA:

2.1.1.186;
Phylogenetic Tree:

2.1.1.186;
Uniprot:
M-CSA:
RHEA:42788 cytidine(2498) in 23S rRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(2498) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]-[S+;H0:4](-[*:5])-[CH3;+0:6]>>[*:1]-[O;H0;+0:2]-[CH3;+0:6].[*:3]-[S;H0;+0:4]-[*:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
YgdE is the 2'-O-ribose methyltransferase RlmM specific for nucleotide C2498 in bacterial 23S rRNA.Purta E, O'Connor M, Bujnicki JM, Douthwaite S2009 Jun19400805