EC number:2.1.1.189

Enzyme

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     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.1 Methyltransferases
ID:2.1.1.189
Description:23S rRNA (uracil(747)-C(5))-methyltransferase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.1.189
BRENDA Enzyme Link: BRENDA 2.1.1.189
KEGG Enzyme Link: KEGG2.1.1.189
BioCyc Enzyme Link: BioCyc 2.1.1.189
ExPASy Enzyme Link: ExPASy2.1.1.189
EC2PDB Enzyme Link: EC2PDB 2.1.1.189
ExplorEnz Enzyme Link: ExplorEnz 2.1.1.189
PRIAM enzyme-specific profiles Link: PRIAM 2.1.1.189
IntEnz Enzyme Link: IntEnz 2.1.1.189
MEDLINE Enzyme Link: MEDLINE 2.1.1.189

EC number:2.1.1.189

MSA:

2.1.1.189;
Phylogenetic Tree:

2.1.1.189;
Uniprot:
M-CSA:
RHEA:42628 S-adenosyl-L-methionine + uridine(747) in 23S rRNA = 5-methyluridine(747) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[S+;H0:2](-[*:3])-[CH3;+0:4].[*:5]:[cH;+0:6]:[*:7]>>[*:1]-[S;H0;+0:2]-[*:3].[*:5]:[c;H0;+0:6](:[*:7])-[CH3;+0:4]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Identifying the methyltransferases for m(5)U747 and m(5)U1939 in 23S rRNA using MALDI mass spectrometry.Madsen CT, Mengel-Jørgensen J, Kirpekar F, Douthwaite S2003 Aug 1512907714