EC number:2.1.1.190
| ID: | 2.1.1.190 |
|---|---|
| Description: | 23S rRNA (uracil(1939)-C(5))-methyltransferase. |
| Alternative Name: |
RNA uridine methyltransferase A. |
| Cath: | 3.40.1350.30; 2.40.50.140; 3.40.50.150; |
3D structure
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.References
External Links
| UniProtKB Enzyme Link: | UniProtKB 2.1.1.190 |
| BRENDA Enzyme Link: | BRENDA 2.1.1.190 |
| KEGG Enzyme Link: | KEGG2.1.1.190 |
| BioCyc Enzyme Link: | BioCyc 2.1.1.190 |
| ExPASy Enzyme Link: | ExPASy2.1.1.190 |
| EC2PDB Enzyme Link: | EC2PDB 2.1.1.190 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.1.1.190 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.1.1.190 |
| IntEnz Enzyme Link: | IntEnz 2.1.1.190 |
| MEDLINE Enzyme Link: | MEDLINE 2.1.1.190 |
EC number:2.1.1.190
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:42908 | S-adenosyl-L-methionine + uridine(1939) in 23S rRNA = 5-methyluridine(1939) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine |
| RULE(radius=1) | [*:1]-[S+;H0:2](-[*:3])-[CH3;+0:4].[*:5]:[cH;+0:6]:[*:7]>>[*:1]-[S;H0;+0:2]-[*:3].[*:5]:[c;H0;+0:6](:[*:7])-[CH3;+0:4] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Crystal structure of RumA, an iron-sulfur cluster containing E. coli ribosomal RNA 5-methyluridine methyltransferase. | Lee TT, Agarwalla S, Stroud RM | 2004 Mar | 15016356 |
| Identifying the methyltransferases for m(5)U747 and m(5)U1939 in 23S rRNA using MALDI mass spectrometry. | Madsen CT, Mengel-Jørgensen J, Kirpekar F, Douthwaite S | 2003 Aug 15 | 12907714 |
| Characterization of the 23 S ribosomal RNA m5U1939 methyltransferase from Escherichia coli. | Agarwalla S, Kealey JT, Santi DV, Stroud RM | 2002 Mar 15 | 11779873 |