EC number:2.1.1.191
| ID: | 2.1.1.191 |
|---|---|
| Description: | 23S rRNA (cytosine(1962)-C(5))-methyltransferase. |
| Alternative Name: |
rRNA large subunit methyltransferase I. |
| Cath: | 3.30.750.80; 2.30.130.10; 3.40.50.150; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.1.1.191 |
| BRENDA Enzyme Link: | BRENDA 2.1.1.191 |
| KEGG Enzyme Link: | KEGG2.1.1.191 |
| BioCyc Enzyme Link: | BioCyc 2.1.1.191 |
| ExPASy Enzyme Link: | ExPASy2.1.1.191 |
| EC2PDB Enzyme Link: | EC2PDB 2.1.1.191 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.1.1.191 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.1.1.191 |
| IntEnz Enzyme Link: | IntEnz 2.1.1.191 |
| MEDLINE Enzyme Link: | MEDLINE 2.1.1.191 |
EC number:2.1.1.191
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:42912 | cytidine(1962) in 23S rRNA + S-adenosyl-L-methionine = 5-methylcytidine(1962) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine |
| RULE(radius=1) | [*:1]-[S+;H0:2](-[*:3])-[CH3;+0:4].[*:5]:[cH;+0:6]:[*:7]>>[*:1]-[S;H0;+0:2]-[*:3].[*:5]:[c;H0;+0:6](:[*:7])-[CH3;+0:4] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Crystal structure of the Escherichia coli 23S rRNA:m5C methyltransferase RlmI (YccW) reveals evolutionary links between RNA modification enzymes. | Sunita S, Tkaczuk KL, Purta E, Kasprzak JM, Douthwaite S, Bujnicki JM, Sivaraman J | 2008 Nov 14 | 18789337 |
| YccW is the m5C methyltransferase specific for 23S rRNA nucleotide 1962. | Purta E, O'Connor M, Bujnicki JM, Douthwaite S | 2008 Nov 14 | 18786544 |