EC number:2.1.1.195

Enzyme

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     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.1 Methyltransferases
ID:2.1.1.195
Description:Cobalt-precorrin-5B (C(1))-methyltransferase.
Alternative Name: Cobalt-precorrin-6A synthase.
Cath: 3.30.1990.10; 3.30.2110.10; 3.40.50.10720;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.1.195
BRENDA Enzyme Link: BRENDA 2.1.1.195
KEGG Enzyme Link: KEGG2.1.1.195
BioCyc Enzyme Link: BioCyc 2.1.1.195
ExPASy Enzyme Link: ExPASy2.1.1.195
EC2PDB Enzyme Link: EC2PDB 2.1.1.195
ExplorEnz Enzyme Link: ExplorEnz 2.1.1.195
PRIAM enzyme-specific profiles Link: PRIAM 2.1.1.195
IntEnz Enzyme Link: IntEnz 2.1.1.195
MEDLINE Enzyme Link: MEDLINE 2.1.1.195

EC number:2.1.1.195

MSA:

2.1.1.195;
Phylogenetic Tree:

2.1.1.195;
Uniprot:
M-CSA:
RHEA:26285 Co-precorrin-5B + S-adenosyl-L-methionine = Co-precorrin-6A + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[N;H0;+0:2]1-[*:3]2-[*:4]-[C;H0;+0:5](-[*:6])=[C;H0;+0:7]3-[*:8]-2=[*:9](-[*:10]-[CH;+0:11]-3-[*:12])-[CH;+0:13]=[C;H0;+0:14]-1-[*:15].[*:16]-[S+;H0:17](-[*:18])-[CH3;+0:19]>>[*:1]-[N+;H0:2]1=[C;H0;+0:14](-[*:15])-[CH2;+0:13]-[*:9]2=[*:8]3-[*:3]-1-[*:4]-[C;H0;+0:5](-[*:6])(-[CH3;+0:19])-[C;H0;+0:7]-3=[C;H0;+0:11](-[*:12])-[*:10]-2.[*:16]-[S;H0;+0:17]-[*:18]
Reaction
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References

TitleAuthorsDatePubMed ID
Genetically engineered production of 1-desmethylcobyrinic acid, 1-desmethylcobyrinic acid a,c-diamide, and cobyrinic acid a,c-diamide in Escherichia coli implies a role for CbiD in C-1 methylation in the anaerobic pathway to cobalamin.Roessner CA, Williams HJ, Scott AI2005 Apr 2915741157