EC number:2.1.1.196

Enzyme

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     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.1 Methyltransferases
ID:2.1.1.196
Description:Cobalt-precorrin-6B (C(15))-methyltransferase (decarboxylating).
Alternative Name: Cobalt-precorrin-6Y (C(15))-methyltransferase (decarboxylating).
Cath: 3.40.50.150;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.1.196
BRENDA Enzyme Link: BRENDA 2.1.1.196
KEGG Enzyme Link: KEGG2.1.1.196
BioCyc Enzyme Link: BioCyc 2.1.1.196
ExPASy Enzyme Link: ExPASy2.1.1.196
EC2PDB Enzyme Link: EC2PDB 2.1.1.196
ExplorEnz Enzyme Link: ExplorEnz 2.1.1.196
PRIAM enzyme-specific profiles Link: PRIAM 2.1.1.196
IntEnz Enzyme Link: IntEnz 2.1.1.196
MEDLINE Enzyme Link: MEDLINE 2.1.1.196

EC number:2.1.1.196

MSA:

2.1.1.196;
Phylogenetic Tree:

2.1.1.196;
Uniprot:
M-CSA:
RHEA:36067 Co-precorrin-6B + S-adenosyl-L-methionine = Co-precorrin-7 + CO2 + S-adenosyl-L-homocysteine
RULE(radius=1) ([*:1]-[CH2;+0:2]-[*:3].[*:4]=[C;H0;+0:5](-[OH;+0:6])-[CH2;+0:7]-[*:8]).[*:9]-[S+;H0:10](-[*:11])-[CH3;+0:12]>>([*:8]-[CH3;+0:7].[*:1]-[CH;+0:2](-[*:3])-[CH3;+0:12]).[*:9]-[S;H0;+0:10]-[*:11].[*:4]=[C;H0;+0:5]=[O;H0;+0:6]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
The crystal structure of MT0146/CbiT suggests that the putative precorrin-8w decarboxylase is a methyltransferase.Keller JP, Smith PM, Benach J, Christendat D, deTitta GT, Hunt JF2002 Nov12429089
Structural characterization of novel cobalt corrinoids synthesized by enzymes of the vitamin B12 anaerobic pathway.Santander PJ, Kajiwara Y, Williams HJ, Scott AI2006 Feb 116198574