EC number:2.1.1.203

Enzyme

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     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.1 Methyltransferases
ID:2.1.1.203
Description:tRNA (cytosine(34)-C(5))-methyltransferase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.1.203
BRENDA Enzyme Link: BRENDA 2.1.1.203
KEGG Enzyme Link: KEGG2.1.1.203
BioCyc Enzyme Link: BioCyc 2.1.1.203
ExPASy Enzyme Link: ExPASy2.1.1.203
EC2PDB Enzyme Link: EC2PDB 2.1.1.203
ExplorEnz Enzyme Link: ExplorEnz 2.1.1.203
PRIAM enzyme-specific profiles Link: PRIAM 2.1.1.203
IntEnz Enzyme Link: IntEnz 2.1.1.203
MEDLINE Enzyme Link: MEDLINE 2.1.1.203

EC number:2.1.1.203

MSA:

2.1.1.203;
Phylogenetic Tree:

2.1.1.203;
Uniprot:
M-CSA:
RHEA:42940 cytidine(34) in tRNA precursor + S-adenosyl-L-methionine = 5-methylcytidine(34) in tRNA precursor + H(+) + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[S+;H0:2](-[*:3])-[CH3;+0:4].[*:5]:[cH;+0:6]:[*:7]>>[*:1]-[S;H0;+0:2]-[*:3].[*:5]:[c;H0;+0:6](:[*:7])-[CH3;+0:4]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Pleiotropic effects of intron removal on base modification pattern of yeast tRNAPhe: an in vitro study.Jiang HQ, Motorin Y, Jin YX, Grosjean H1997 Jul 159207014
Effect of intron mutations on processing and function of Saccharomyces cerevisiae SUP53 tRNA in vitro and in vivo.Strobel MC, Abelson J1986 Jul3537724
Cysteine of sequence motif VI is essential for nucleophilic catalysis by yeast tRNA m5C methyltransferase.Walbott H, Husson C, Auxilien S, Golinelli-Pimpaneau B2007 Jul17475914
Multisite-specific tRNA:m5C-methyltransferase (Trm4) in yeast Saccharomyces cerevisiae: identification of the gene and substrate specificity of the enzyme.Motorin Y, Grosjean H1999 Aug10445884