EC number:2.1.1.205

Enzyme

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     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.1 Methyltransferases
ID:2.1.1.205
Description:tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.1.205
BRENDA Enzyme Link: BRENDA 2.1.1.205
KEGG Enzyme Link: KEGG2.1.1.205
BioCyc Enzyme Link: BioCyc 2.1.1.205
ExPASy Enzyme Link: ExPASy2.1.1.205
EC2PDB Enzyme Link: EC2PDB 2.1.1.205
ExplorEnz Enzyme Link: ExplorEnz 2.1.1.205
PRIAM enzyme-specific profiles Link: PRIAM 2.1.1.205
IntEnz Enzyme Link: IntEnz 2.1.1.205
MEDLINE Enzyme Link: MEDLINE 2.1.1.205

EC number:2.1.1.205

MSA:

2.1.1.205;
Phylogenetic Tree:

2.1.1.205;
Uniprot:
M-CSA:
RHEA:42396 cytidine(32)/guanosine(34) in tRNA + 2 S-adenosyl-L-methionine = 2'-O-methylcytidine(32)/2'-O-methylguanosine(34) in tRNA + 2 H(+) + 2 S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]-[OH;+0:4].[*:5]-[S+;H0:6](-[*:7])-[CH3;+0:8].[*:9]-[S+;H0:10](-[*:11])-[CH3;+0:12]>>[*:1]-[O;H0;+0:2]-[CH3;+0:8].[*:3]-[O;H0;+0:4]-[CH3;+0:12].[*:5]-[S;H0;+0:6]-[*:7].[*:9]-[S;H0;+0:10]-[*:11]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Trm7p catalyses the formation of two 2'-O-methylriboses in yeast tRNA anticodon loop.Pintard L, Lecointe F, Bujnicki JM, Bonnerot C, Grosjean H, Lapeyre B2002 Apr 211927565