| ID: | 2.1.1.207 |
|---|---|
| Description: | tRNA (cytidine(34)-2'-O)-methyltransferase. |
| Alternative Name: |
tRNA methyltransferase L. methyltransferase. tRNA (cytidine(34)/5-carboxymethylaminomethyluridine(34)-2'-O)- |
| Cath: | 3.40.1280.10; |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| UniProtKB Enzyme Link: | UniProtKB 2.1.1.207 |
| BRENDA Enzyme Link: | BRENDA 2.1.1.207 |
| KEGG Enzyme Link: | KEGG2.1.1.207 |
| BioCyc Enzyme Link: | BioCyc 2.1.1.207 |
| ExPASy Enzyme Link: | ExPASy2.1.1.207 |
| EC2PDB Enzyme Link: | EC2PDB 2.1.1.207 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.1.1.207 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.1.1.207 |
| IntEnz Enzyme Link: | IntEnz 2.1.1.207 |
| MEDLINE Enzyme Link: | MEDLINE 2.1.1.207 |
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:43088 | 5-carboxymethylaminomethyluridine(34) in tRNA(Leu) + S-adenosyl-L-methionine = 5-carboxymethylaminomethyl-2'-O-methyluridine(34) in tRNA(Leu) + H(+) + S-adenosyl-L-homocysteine |
| RULE(radius=1) | [*:1]-[OH;+0:2].[*:3]-[S+;H0:4](-[*:5])-[CH3;+0:6]>>[*:1]-[O;H0;+0:2]-[CH3;+0:6].[*:3]-[S;H0;+0:4]-[*:5] |
| Reaction | ![]() |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| YibK is the 2'-O-methyltransferase TrmL that modifies the wobble nucleotide in Escherichia coli tRNA(Leu) isoacceptors. | Benítez-Páez A, Villarroya M, Douthwaite S, Gabaldón T, Armengod ME | 2010 Nov | 20855540 |
| RHEA:43084 | cytidine(34) in tRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(34) in tRNA + H(+) + S-adenosyl-L-homocysteine |
| RULE(radius=1) | [*:1]-[OH;+0:2].[*:3]-[S+;H0:4](-[*:5])-[CH3;+0:6]>>[*:1]-[O;H0;+0:2]-[CH3;+0:6].[*:3]-[S;H0;+0:4]-[*:5] |
| Reaction | ![]() |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| YibK is the 2'-O-methyltransferase TrmL that modifies the wobble nucleotide in Escherichia coli tRNA(Leu) isoacceptors. | Benítez-Páez A, Villarroya M, Douthwaite S, Gabaldón T, Armengod ME | 2010 Nov | 20855540 |