Enzyme

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     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.1 Methyltransferases
ID:2.1.1.207
Description:tRNA (cytidine(34)-2'-O)-methyltransferase.
Alternative Name: tRNA methyltransferase L.
methyltransferase.
tRNA (cytidine(34)/5-carboxymethylaminomethyluridine(34)-2'-O)-
Cath: 3.40.1280.10;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.1.207
BRENDA Enzyme Link: BRENDA 2.1.1.207
KEGG Enzyme Link: KEGG2.1.1.207
BioCyc Enzyme Link: BioCyc 2.1.1.207
ExPASy Enzyme Link: ExPASy2.1.1.207
EC2PDB Enzyme Link: EC2PDB 2.1.1.207
ExplorEnz Enzyme Link: ExplorEnz 2.1.1.207
PRIAM enzyme-specific profiles Link: PRIAM 2.1.1.207
IntEnz Enzyme Link: IntEnz 2.1.1.207
MEDLINE Enzyme Link: MEDLINE 2.1.1.207
MSA:

2.1.1.207;

Phylogenetic Tree:

2.1.1.207;

Uniprot:
M-CSA:
RHEA:43088 5-carboxymethylaminomethyluridine(34) in tRNA(Leu) + S-adenosyl-L-methionine = 5-carboxymethylaminomethyl-2'-O-methyluridine(34) in tRNA(Leu) + H(+) + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]-[S+;H0:4](-[*:5])-[CH3;+0:6]>>[*:1]-[O;H0;+0:2]-[CH3;+0:6].[*:3]-[S;H0;+0:4]-[*:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
YibK is the 2'-O-methyltransferase TrmL that modifies the wobble nucleotide in Escherichia coli tRNA(Leu) isoacceptors.Benítez-Páez A, Villarroya M, Douthwaite S, Gabaldón T, Armengod ME2010 Nov20855540

RHEA:43084 cytidine(34) in tRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(34) in tRNA + H(+) + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]-[S+;H0:4](-[*:5])-[CH3;+0:6]>>[*:1]-[O;H0;+0:2]-[CH3;+0:6].[*:3]-[S;H0;+0:4]-[*:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
YibK is the 2'-O-methyltransferase TrmL that modifies the wobble nucleotide in Escherichia coli tRNA(Leu) isoacceptors.Benítez-Páez A, Villarroya M, Douthwaite S, Gabaldón T, Armengod ME2010 Nov20855540