EC number:2.1.1.217

Enzyme

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     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.1 Methyltransferases
ID:2.1.1.217
Description:tRNA (adenine(22)-N(1))-methyltransferase.
Cath: 1.10.287.1890; 3.40.50.150;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.1.217
BRENDA Enzyme Link: BRENDA 2.1.1.217
KEGG Enzyme Link: KEGG2.1.1.217
BioCyc Enzyme Link: BioCyc 2.1.1.217
ExPASy Enzyme Link: ExPASy2.1.1.217
EC2PDB Enzyme Link: EC2PDB 2.1.1.217
ExplorEnz Enzyme Link: ExplorEnz 2.1.1.217
PRIAM enzyme-specific profiles Link: PRIAM 2.1.1.217
IntEnz Enzyme Link: IntEnz 2.1.1.217
MEDLINE Enzyme Link: MEDLINE 2.1.1.217

EC number:2.1.1.217

MSA:

2.1.1.217;
Phylogenetic Tree:

2.1.1.217;
Uniprot:
M-CSA:
RHEA:43144 adenosine(22) in tRNA + S-adenosyl-L-methionine = H(+) + N(1)-methyladenosine(22) in tRNA + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[S+;H0:2](-[*:3])-[CH3;+0:4].[*:5]:[c;H0;+0:6](-[NH2;+0:7]):[n;H0;+0:8]:[*:9]>>[*:1]-[S;H0;+0:2]-[*:3].[*:5]:[c;H0;+0:6](=[NH;+0:7]):[n;H0;+0:8](:[*:9])-[CH3;+0:4]
Reaction
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References

TitleAuthorsDatePubMed ID
Crystal structure of Streptococcus pneumoniae Sp1610, a putative tRNA methyltransferase, in complex with S-adenosyl-L-methionine.Ta HM, Kim KK2010 Mar20052680
The YqfN protein of Bacillus subtilis is the tRNA: m1A22 methyltransferase (TrmK).Roovers M, Kaminska KH, Tkaczuk KL, Gigot D, Droogmans L, Bujnicki JM2008 Jun18420655