EC number:2.1.1.218

Enzyme

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     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.1 Methyltransferases
ID:2.1.1.218
Description:tRNA (adenine(9)-N(1))-methyltransferase.
Alternative Name: tRNA(m(1)G(9)/m(1)A(9))-methyltransferase.
tRNA m(1)A(9)-methyltransferase.
Cath: 3.40.1280.30;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.1.218
BRENDA Enzyme Link: BRENDA 2.1.1.218
KEGG Enzyme Link: KEGG2.1.1.218
BioCyc Enzyme Link: BioCyc 2.1.1.218
ExPASy Enzyme Link: ExPASy2.1.1.218
EC2PDB Enzyme Link: EC2PDB 2.1.1.218
ExplorEnz Enzyme Link: ExplorEnz 2.1.1.218
PRIAM enzyme-specific profiles Link: PRIAM 2.1.1.218
IntEnz Enzyme Link: IntEnz 2.1.1.218
MEDLINE Enzyme Link: MEDLINE 2.1.1.218

EC number:2.1.1.218

MSA:

2.1.1.218;
Phylogenetic Tree:

2.1.1.218;
Uniprot:
M-CSA:
RHEA:43148 adenosine(9) in tRNA + S-adenosyl-L-methionine = H(+) + N(1)-methyladenosine(9) in tRNA + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[S+;H0:2](-[*:3])-[CH3;+0:4].[*:5]:[c;H0;+0:6](-[NH2;+0:7]):[n;H0;+0:8]:[*:9]>>[*:1]-[S;H0;+0:2]-[*:3].[*:5]:[c;H0;+0:6](=[NH;+0:7]):[n;H0;+0:8](:[*:9])-[CH3;+0:4]
Reaction
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References

TitleAuthorsDatePubMed ID
New archaeal methyltransferases forming 1-methyladenosine or 1-methyladenosine and 1-methylguanosine at position 9 of tRNA.Kempenaers M, Roovers M, Oudjama Y, Tkaczuk KL, Bujnicki JM, Droogmans L2010 Oct20525789