EC number:2.1.1.225

Enzyme

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     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.1 Methyltransferases
ID:2.1.1.225
Description:tRNA:m(4)X modification enzyme.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.1.225
BRENDA Enzyme Link: BRENDA 2.1.1.225
KEGG Enzyme Link: KEGG2.1.1.225
BioCyc Enzyme Link: BioCyc 2.1.1.225
ExPASy Enzyme Link: ExPASy2.1.1.225
EC2PDB Enzyme Link: EC2PDB 2.1.1.225
ExplorEnz Enzyme Link: ExplorEnz 2.1.1.225
PRIAM enzyme-specific profiles Link: PRIAM 2.1.1.225
IntEnz Enzyme Link: IntEnz 2.1.1.225
MEDLINE Enzyme Link: MEDLINE 2.1.1.225

EC number:2.1.1.225

MSA:

2.1.1.225;
Phylogenetic Tree:

2.1.1.225;
Uniprot:
M-CSA:
RHEA:43196 adenosine(4) in tRNA(His) + S-adenosyl-L-methionine = 2'-O-methyladenosine(4) in tRNA(His) + H(+) + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]-[S+;H0:4](-[*:5])-[CH3;+0:6]>>[*:1]-[O;H0;+0:2]-[CH3;+0:6].[*:3]-[S;H0;+0:4]-[*:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
The 2'-O-methyltransferase responsible for modification of yeast tRNA at position 4.Wilkinson ML, Crary SM, Jackman JE, Grayhack EJ, Phizicky EM2007 Mar17242307
RHEA:43192 cytidine(4) in tRNA(Gly)(GCC) + S-adenosyl-L-methionine = 2'-O-methylcytidine(4) in tRNA(Gly)(GCC) + H(+) + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]-[S+;H0:4](-[*:5])-[CH3;+0:6]>>[*:1]-[O;H0;+0:2]-[CH3;+0:6].[*:3]-[S;H0;+0:4]-[*:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
The 2'-O-methyltransferase responsible for modification of yeast tRNA at position 4.Wilkinson ML, Crary SM, Jackman JE, Grayhack EJ, Phizicky EM2007 Mar17242307
RHEA:32767 cytidine(4) in tRNA(Pro) + S-adenosyl-L-methionine = 2'-O-methylcytidine(4) in tRNA(Pro) + H(+) + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[OH;+0:2].[*:3]-[S+;H0:4](-[*:5])-[CH3;+0:6]>>[*:1]-[O;H0;+0:2]-[CH3;+0:6].[*:3]-[S;H0;+0:4]-[*:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
The 2'-O-methyltransferase responsible for modification of yeast tRNA at position 4.Wilkinson ML, Crary SM, Jackman JE, Grayhack EJ, Phizicky EM2007 Mar17242307