EC number:2.1.1.227
| ID: | 2.1.1.227 |
|---|---|
| Description: | 16S rRNA (cytidine(1409)-2'-O)-methyltransferase. |
| Cath: | 3.40.50.150; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.1.1.227 |
| BRENDA Enzyme Link: | BRENDA 2.1.1.227 |
| KEGG Enzyme Link: | KEGG2.1.1.227 |
| BioCyc Enzyme Link: | BioCyc 2.1.1.227 |
| ExPASy Enzyme Link: | ExPASy2.1.1.227 |
| EC2PDB Enzyme Link: | EC2PDB 2.1.1.227 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.1.1.227 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.1.1.227 |
| IntEnz Enzyme Link: | IntEnz 2.1.1.227 |
| MEDLINE Enzyme Link: | MEDLINE 2.1.1.227 |
EC number:2.1.1.227
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:43204 | cytidine(1409) in 16S rRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(1409) in 16S rRNA + H(+) + S-adenosyl-L-homocysteine |
| RULE(radius=1) | [*:1]-[OH;+0:2].[*:3]-[S+;H0:4](-[*:5])-[CH3;+0:6]>>[*:1]-[O;H0;+0:2]-[CH3;+0:6].[*:3]-[S;H0;+0:4]-[*:5] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Capreomycin binds across the ribosomal subunit interface using tlyA-encoded 2'-O-methylations in 16S and 23S rRNAs. | Johansen SK, Maus CE, Plikaytis BB, Douthwaite S | 2006 Jul 21 | 16857584 |
| Mutation of tlyA confers capreomycin resistance in Mycobacterium tuberculosis. | Maus CE, Plikaytis BB, Shinnick TM | 2005 Feb | 15673735 |