EC number:2.1.1.238
| ID: | 2.1.1.238 |
|---|---|
| Description: | Mycinamicin VI 2''-O-methyltransferase. |
| Cath: | 3.30.1050.30; 3.40.50.150; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 2.1.1.238 |
| BRENDA Enzyme Link: | BRENDA 2.1.1.238 |
| KEGG Enzyme Link: | KEGG2.1.1.238 |
| BioCyc Enzyme Link: | BioCyc 2.1.1.238 |
| ExPASy Enzyme Link: | ExPASy2.1.1.238 |
| EC2PDB Enzyme Link: | EC2PDB 2.1.1.238 |
| ExplorEnz Enzyme Link: | ExplorEnz 2.1.1.238 |
| PRIAM enzyme-specific profiles Link: | PRIAM 2.1.1.238 |
| IntEnz Enzyme Link: | IntEnz 2.1.1.238 |
| MEDLINE Enzyme Link: | MEDLINE 2.1.1.238 |
EC number:2.1.1.238
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:31643 | mycinamicin VI + S-adenosyl-L-methionine = H(+) + mycinamicin III + S-adenosyl-L-homocysteine |
| RULE(radius=1) | [*:1]-[OH;+0:2].[*:3]-[S+;H0:4](-[*:5])-[CH3;+0:6]>>[*:1]-[O;H0;+0:2]-[CH3;+0:6].[*:3]-[S;H0;+0:4]-[*:5] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| A new structural form in the SAM/metal-dependent o‑methyltransferase family: MycE from the mycinamicin biosynthetic pathway. | Akey DL, Li S, Konwerski JR, Confer LA, Bernard SM, Anzai Y, Kato F, Sherman DH, Smith JL | 2011 Oct 21 | 21884704 |
| Functional analysis of MycE and MycF, two O-methyltransferases involved in the biosynthesis of mycinamicin macrolide antibiotics. | Li S, Anzai Y, Kinoshita K, Kato F, Sherman DH | 2009 May 25 | 19415708 |