EC number:2.1.1.248

Enzyme

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EC Tree
     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.1 Methyltransferases
ID:2.1.1.248
Description:[Methylamine--corrinoid protein] Co-methyltransferase.
Alternative Name: Monomethylamine methyltransferase.
Cath: 3.20.20.460;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.1.248
BRENDA Enzyme Link: BRENDA 2.1.1.248
KEGG Enzyme Link: KEGG2.1.1.248
BioCyc Enzyme Link: BioCyc 2.1.1.248
ExPASy Enzyme Link: ExPASy2.1.1.248
EC2PDB Enzyme Link: EC2PDB 2.1.1.248
ExplorEnz Enzyme Link: ExplorEnz 2.1.1.248
PRIAM enzyme-specific profiles Link: PRIAM 2.1.1.248
IntEnz Enzyme Link: IntEnz 2.1.1.248
MEDLINE Enzyme Link: MEDLINE 2.1.1.248

EC number:2.1.1.248

MSA:

2.1.1.248;
Phylogenetic Tree:

2.1.1.248;
Uniprot:
M-CSA:
RHEA:26059 [Co(I) methylamine-specific corrinoid protein] + H(+) + methylamine = [methyl-Co(III) methylamine-specific corrinoid protein] + NH4(+)
RULE(radius=1) [CH3;+0:1]-[NH2;+0:2].[Co+;H0:3].[H+;H0:4]>>[CH3;+0:1]-[Co+2;H0:3].[NH3;+0:2]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Clustered genes encoding the methyltransferases of methanogenesis from monomethylamine.Burke SA, Lo SL, Krzycki JA1998 Jul9642198
Reconstitution of Monomethylamine:Coenzyme M methyl transfer with a corrinoid protein and two methyltransferases purified from Methanosarcina barkeri.Burke SA, Krzycki JA1997 Jun 279195968
Function of genetically encoded pyrrolysine in corrinoid-dependent methylamine methyltransferases.Krzycki JA2004 Oct15450490