EC number:2.1.1.250

Enzyme

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     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.1 Methyltransferases
ID:2.1.1.250
Description:[Trimethylamine--corrinoid protein] Co-methyltransferase.
Alternative Name: Trimethylamine methyltransferase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.1.250
BRENDA Enzyme Link: BRENDA 2.1.1.250
KEGG Enzyme Link: KEGG2.1.1.250
BioCyc Enzyme Link: BioCyc 2.1.1.250
ExPASy Enzyme Link: ExPASy2.1.1.250
EC2PDB Enzyme Link: EC2PDB 2.1.1.250
ExplorEnz Enzyme Link: ExplorEnz 2.1.1.250
PRIAM enzyme-specific profiles Link: PRIAM 2.1.1.250
IntEnz Enzyme Link: IntEnz 2.1.1.250
MEDLINE Enzyme Link: MEDLINE 2.1.1.250

EC number:2.1.1.250

MSA:

2.1.1.250;
Phylogenetic Tree:

2.1.1.250;
Uniprot:
M-CSA:
RHEA:39287 [Co(I) trimethylamine-specific corrinoid protein] + H(+) + trimethylamine = [methyl-Co(III) trimethylamine-specific corrinoid protein] + dimethylamine
RULE(radius=1) [*:1]-[N;H0;+0:2](-[*:3])-[CH3;+0:4].[Co+;H0:5].[H+;H0:6]>>[*:1]-[NH;+0:2]-[*:3].[CH3;+0:4]-[Co+2;H0:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Reconstitution of trimethylamine-dependent coenzyme M methylation with the trimethylamine corrinoid protein and the isozymes of methyltransferase II from Methanosarcina barkeri.Ferguson DJ Jr, Krzycki JA1997 Feb9006042
Function of genetically encoded pyrrolysine in corrinoid-dependent methylamine methyltransferases.Krzycki JA2004 Oct15450490