Enzyme

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EC Tree
     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.1 Methyltransferases
ID:2.1.1.255
Description:Geranyl diphosphate 2-C-methyltransferase.
Alternative Name: MGPPS.
GPPMT.
GPP methyltransferase.
Geranyl pyrophosphate methyltransferase.
2-methyl-GPP synthase.
Cath: 3.40.50.150;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.1.255
BRENDA Enzyme Link: BRENDA 2.1.1.255
KEGG Enzyme Link: KEGG2.1.1.255
BioCyc Enzyme Link: BioCyc 2.1.1.255
ExPASy Enzyme Link: ExPASy2.1.1.255
EC2PDB Enzyme Link: EC2PDB 2.1.1.255
ExplorEnz Enzyme Link: ExplorEnz 2.1.1.255
PRIAM enzyme-specific profiles Link: PRIAM 2.1.1.255
IntEnz Enzyme Link: IntEnz 2.1.1.255
MEDLINE Enzyme Link: MEDLINE 2.1.1.255
MSA:

2.1.1.255;

Phylogenetic Tree:

2.1.1.255;

Uniprot:
M-CSA:
RHEA:32519 (2E)-geranyl diphosphate + S-adenosyl-L-methionine = (E)-2-methylgeranyl diphosphate + H(+) + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[CH;+0:2]=[*:3].[*:4]-[S+;H0:5](-[*:6])-[CH3;+0:7]>>[*:1]-[C;H0;+0:2](=[*:3])-[CH3;+0:7].[*:4]-[S;H0;+0:5]-[*:6]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Crystallization and preliminary X-ray crystallographic study of a methyltransferase involved in 2-methylisoborneol biosynthesis in Streptomyces lasaliensis.Ariyawutthiphan O, Ose T, Tsuda M, Gao Y, Yao M, Minami A, Oikawa H, Tanaka I2011 Mar 121393856
Biosynthesis of 2-methylisoborneol in cyanobacteria.Giglio S, Chou WK, Ikeda H, Cane DE, Monis PT2011 Feb 121174459
Biochemistry and molecular genetics of the biosynthesis of the earthy odorant methylisoborneol in Streptomyces coelicolor.Wang CM, Cane DE2008 Jul 1618563898
Identification and functional analysis of genes controlling biosynthesis of 2-methylisoborneol.Komatsu M, Tsuda M, Omura S, Oikawa H, Ikeda H2008 May 2718492804