EC number:2.1.1.256

Enzyme

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     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.1 Methyltransferases
ID:2.1.1.256
Description:tRNA (guanine(6)-N(2))-methyltransferase.
Alternative Name: Methyltransferase Trm14.
M(2)G6 methyltransferase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.1.256
BRENDA Enzyme Link: BRENDA 2.1.1.256
KEGG Enzyme Link: KEGG2.1.1.256
BioCyc Enzyme Link: BioCyc 2.1.1.256
ExPASy Enzyme Link: ExPASy2.1.1.256
EC2PDB Enzyme Link: EC2PDB 2.1.1.256
ExplorEnz Enzyme Link: ExplorEnz 2.1.1.256
PRIAM enzyme-specific profiles Link: PRIAM 2.1.1.256
IntEnz Enzyme Link: IntEnz 2.1.1.256
MEDLINE Enzyme Link: MEDLINE 2.1.1.256

EC number:2.1.1.256

MSA:

2.1.1.256;
Phylogenetic Tree:

2.1.1.256;
Uniprot:
M-CSA:
RHEA:51116 guanosine(6) in tRNA + S-adenosyl-L-methionine = H(+) + N(2)-methylguanosine(6) in tRNA + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[NH2;+0:2].[*:3]-[S+;H0:4](-[*:5])-[CH3;+0:6]>>[*:1]-[NH;+0:2]-[CH3;+0:6].[*:3]-[S;H0;+0:4]-[*:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Formation of m2G6 in Methanocaldococcus jannaschii tRNA catalyzed by the novel methyltransferase Trm14.Menezes S, Gaston KW, Krivos KL, Apolinario EE, Reich NO, Sowers KR, Limbach PA, Perona JJ2011 Sep 121693558