EC number:2.1.1.262

Enzyme

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     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.1 Methyltransferases
ID:2.1.1.262
Description:Squalene methyltransferase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.1.262
BRENDA Enzyme Link: BRENDA 2.1.1.262
KEGG Enzyme Link: KEGG2.1.1.262
BioCyc Enzyme Link: BioCyc 2.1.1.262
ExPASy Enzyme Link: ExPASy2.1.1.262
EC2PDB Enzyme Link: EC2PDB 2.1.1.262
ExplorEnz Enzyme Link: ExplorEnz 2.1.1.262
PRIAM enzyme-specific profiles Link: PRIAM 2.1.1.262
IntEnz Enzyme Link: IntEnz 2.1.1.262
MEDLINE Enzyme Link: MEDLINE 2.1.1.262

EC number:2.1.1.262

MSA:

2.1.1.262;
Phylogenetic Tree:

2.1.1.262;
Uniprot:
M-CSA:
RHEA:34643 2 S-adenosyl-L-methionine + squalene = 3,22-dimethyl-1,2,23,24-tetradehydro-2,3,22,23-tetrahydrosqualene + 2 H(+) + 2 S-adenosyl-L-homocysteine
RULE(radius=1) ([*:1]-[C;H0;+0:2](-[CH3;+0:3])=[CH;+0:4]-[*:5].[*:6]-[CH;+0:7]=[C;H0;+0:8](-[*:9])-[CH3;+0:10]).[*:11]-[S+;H0:12](-[*:13])-[CH3;+0:14].[*:15]-[S+;H0:16](-[*:17])-[CH3;+0:18]>>([*:1]-[C;H0;+0:2](=[CH2;+0:3])-[CH;+0:4](-[*:5])-[CH3;+0:14].[*:6]-[CH;+0:7](-[CH3;+0:18])-[C;H0;+0:8](-[*:9])=[CH2;+0:10]).[*:11]-[S;H0;+0:12]-[*:13].[*:15]-[S;H0;+0:16]-[*:17]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Functional identification of triterpene methyltransferases from Botryococcus braunii race B.Niehaus TD, Kinison S, Okada S, Yeo YS, Bell SA, Cui P, Devarenne TP, Chappell J2012 Mar 922241476