Enzyme

Download
EC Tree
     2. Transferases
        2.1 Transferring one-carbon groups
            2.1.1 Methyltransferases
ID:2.1.1.266
Description:23S rRNA (adenine(2030)-N(6))-methyltransferase.
Alternative Name: M(6)A(2030) methyltransferase.
Cath: 3.40.50.150;

3D structure

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.

References

External Links

UniProtKB Enzyme Link: UniProtKB 2.1.1.266
BRENDA Enzyme Link: BRENDA 2.1.1.266
KEGG Enzyme Link: KEGG2.1.1.266
BioCyc Enzyme Link: BioCyc 2.1.1.266
ExPASy Enzyme Link: ExPASy2.1.1.266
EC2PDB Enzyme Link: EC2PDB 2.1.1.266
ExplorEnz Enzyme Link: ExplorEnz 2.1.1.266
PRIAM enzyme-specific profiles Link: PRIAM 2.1.1.266
IntEnz Enzyme Link: IntEnz 2.1.1.266
MEDLINE Enzyme Link: MEDLINE 2.1.1.266
MSA:

2.1.1.266;

Phylogenetic Tree:

2.1.1.266;

Uniprot:
M-CSA:
RHEA:43736 adenosine(2030) in 23S rRNA + S-adenosyl-L-methionine = H(+) + N(6)-methyladenosine(2030) in 23S rRNA + S-adenosyl-L-homocysteine
RULE(radius=1) [*:1]-[NH2;+0:2].[*:3]-[S+;H0:4](-[*:5])-[CH3;+0:6]>>[*:1]-[NH;+0:2]-[CH3;+0:6].[*:3]-[S;H0;+0:4]-[*:5]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
The last rRNA methyltransferase of E. coli revealed: the yhiR gene encodes adenine-N6 methyltransferase specific for modification of A2030 of 23S ribosomal RNA.Golovina AY, Dzama MM, Osterman IA, Sergiev PV, Serebryakova MV, Bogdanov AA, Dontsova OA2012 Sep22847818